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1. (WO2003062245) FUSED BICYCLIC PYRIMIDINE DERIVATIVES

Pub. No.:    WO/2003/062245    International Application No.:    PCT/JP2003/000263
Publication Date: Jul 31, 2003 International Filing Date: Jan 15, 2003
IPC: A61K 31/5365
C07D 498/04
Applicants: KYORIN PHARMACEUTICAL CO., LTD.

SETO, Shigeki

TANIOKA, Asao

IKEDA, Makoto

IZAWA, Shigeru

Inventors: SETO, Shigeki

TANIOKA, Asao

IKEDA, Makoto

IZAWA, Shigeru

Title: FUSED BICYCLIC PYRIMIDINE DERIVATIVES
Abstract:
It is intended to provide novel fused bicyclic pyrimidine derivatives represented by the general formula (1), which have a tachykinin receptor antagonism, in particular, an NK1 receptor antagonism, or salts thereof: (1) wherein the rings A and B represent each a benzene ring optionally having 1 to 3 substituents (wherein 2 adjacent substituents may be bonded to each other to form a ring); the ring C represents a nitrogen-containing ring; m is 1 or 2; and n is 2 or 3.