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Machine translation
1. (WO2003062235) MODULATORS OF ACETYLCHOLINE RECEPTORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/062235    International Application No.:    PCT/US2002/021296
Publication Date: 31.07.2003 International Filing Date: 29.07.2002
Chapter 2 Demand Filed:    08.01.2003    
IPC:
A61K 31/46 (2006.01), A61K 31/55 (2006.01), C07D 451/04 (2006.01), C07D 451/14 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center, Indianapolis, IN 46285 (US) (For All Designated States Except US).
ASTLES, Peter, Charles [GB/GB]; (GB) (For US Only).
BAKER, Stephen, Richard [GB/GB]; (GB) (For US Only).
KEENAN, Martine [GB/GB]; (GB) (For US Only).
VERNIER, Jean, Michel [FR/US]; (US) (For US Only).
SANDERSON, Adam, Jan [GB/GB]; (GB) (For US Only).
CUBE, Rowena, Villanueva [US/US]; (US) (For US Only).
MARTINEZ-PEREZ, Jose, Antonio [ES/ES]; (ES) (For US Only).
MATEO HERRANZ, Ana, Isabel [ES/ES]; (ES) (For US Only).
DELL, Colin, Peter [GB/GB]; (GB) (For US Only).
GUTIERREZ, Sonia [ES/ES]; (ES) (For US Only).
PRIETO, Lourdes [ES/ES]; (ES) (For US Only).
SMITH, Colin, William [GB/GB]; (GB) (For US Only)
Inventors: ASTLES, Peter, Charles; (GB).
BAKER, Stephen, Richard; (GB).
KEENAN, Martine; (GB).
VERNIER, Jean, Michel; (US).
SANDERSON, Adam, Jan; (GB).
CUBE, Rowena, Villanueva; (US).
MARTINEZ-PEREZ, Jose, Antonio; (ES).
MATEO HERRANZ, Ana, Isabel; (ES).
DELL, Colin, Peter; (GB).
GUTIERREZ, Sonia; (ES).
PRIETO, Lourdes; (ES).
SMITH, Colin, William; (GB)
Agent: SALES, James, J.; Eli Lilly and Company, P. O. Box 6288, Indianapolis, IN 46206-6288 (US)
Priority Data:
60/350,152 17.01.2002 US
Title (EN) MODULATORS OF ACETYLCHOLINE RECEPTORS
(FR) MODULATEURS DE RECEPTEURS DE L'ACETYLCHOLINE
Abstract: front page image
(EN)The present invention relates to compounds that modulate neurotransmission by promoting the release of neurotransmitters such as acetylcholine, dopamine and norepinephrine. More particularly, the present invention relates to thio-bridged aryl compounds that are capable of modulating acetylcholine receptors and pharmaceutical compositions comprising such compounds. The compounds disclosed are useful for the treatment of dysfunctions of the central and autonomic nervous systems.
(FR)L'invention concerne des composés qui modulent la neurotransmission en favorisant la libération de neurotransmetteurs tels que l'acétylcholine, la dopamine et la norépinéphrine. La présente invention concerne en particulier des composés aryle à pont thio, capables de moduler des récepteurs d'acétylcholine, ainsi que des préparations pharmaceutiques comprenant ces composés. Les composés selon l'invention s'avèrent utiles pour traiter les dysfonctionnements des systèmes nerveux central et autonome.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)