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1. (WO2003059343) DRUG COMPOSITIONS WITH INDOLE ALKALOIDS FOR THE TREATMENT OF AIDS

Pub. No.:    WO/2003/059343    International Application No.:    PCT/BR2002/000193
Publication Date: Jul 24, 2003 International Filing Date: Dec 26, 2002
IPC: A61K 31/407
Applicants: FUNDACÃO OSWALDO CRUZ - FIOCRUZ
BOU-HABIB, Dumith, Cherquer
CASTRO, Bernardo, Galvão
DA SILVA, Edinete, Melo
BOU-HABIB, Elvira Maria Saraiva Chequer
KUEHNE, Martin, E.
Inventors: BOU-HABIB, Dumith, Cherquer
CASTRO, Bernardo, Galvão
DA SILVA, Edinete, Melo
BOU-HABIB, Elvira Maria Saraiva Chequer
KUEHNE, Martin, E.
Title: DRUG COMPOSITIONS WITH INDOLE ALKALOIDS FOR THE TREATMENT OF AIDS
Abstract:
The present invention refers to the use of iboga type indole alkaloids, especially coronaridine and its derivative 18-methoxy coronaridine, in the preparation of medications capable of inhibiting HIV virus action. One of the embodiments of the present invention is related to a pharmaceutical composition for the treatment of AIDS, containing coronaridine and a pharmaceutically acceptable vehicle. Another embodiment of the present invention refers to a pharmaceutical composition for the treatment of AIDS containing coronaridine analogues, especially 18-methoxy coronaridine and a pharmaceutically acceptable vehicle.