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1. (WO2003059258) COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE

Pub. No.:    WO/2003/059258    International Application No.:    PCT/US2002/040996
Publication Date: Jul 24, 2003 International Filing Date: Dec 20, 2002
IPC: C07D 213/65
C07D 261/18
C07D 333/38
C07D 401/12
C07D 409/12
C07D 413/12
Applicants: CYTOKINETICS, INC.
MALIK, Fady
TOMASI, Adam, Lewis
FENG, Bainian
KRAYNACK, Erica, Anne
ELIAS, Kathleen
LU, Pu-Ping
SMITH, Whitney, Walter
QIAN, Xiangping
MORGANS, David, J., Jr.
Inventors: MALIK, Fady
TOMASI, Adam, Lewis
FENG, Bainian
KRAYNACK, Erica, Anne
ELIAS, Kathleen
LU, Pu-Ping
SMITH, Whitney, Walter
QIAN, Xiangping
MORGANS, David, J., Jr.
Title: COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE
Abstract:
Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.