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1. (WO2003059153) COMPOSITION AND IMAGING METHODS FOR PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION OF THERAPEUTIC DELIVERY SYSTEM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/059153    International Application No.:    PCT/US2003/001179
Publication Date: 24.07.2003 International Filing Date: 15.01.2003
Chapter 2 Demand Filed:    02.06.2003    
IPC:
A61B 1/00 (2006.01), A61K 48/00 (2006.01), C12N 15/63 (2006.01)
Applicants: VANDERBILT UNIVERSITY [US/US]; 1207-17th Avenue South, Suite 105, Nashville, TN 37212 (US) (For All Designated States Except US).
HALLAHAN, Dennis, E. [US/US]; (US) (For US Only)
Inventors: HALLAHAN, Dennis, E.; (US)
Agent: TAYLOR, Arles, A., Jr.; Jenkins & Wilson, P.A., Suite 1400, University Tower, 3100 Tower Boulevard, Durham, NC 27707 (US)
Priority Data:
60/348,945 15.01.2002 US
Title (EN) COMPOSITION AND IMAGING METHODS FOR PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION OF THERAPEUTIC DELIVERY SYSTEM
(FR) COMPOSITION ET PROCEDES D'IMAGERIE POUR UNE EVALUATION PHARMACOCINETIQUE ET PHARMACODYNAMIQUE D'UN SYSTEME D'ADMINISTRATION THERAPEUTIQUE
Abstract: front page image
(EN)A halogen-labeled gene therapy construct that includes halogen labeled nucleic acids, methods for preparing a halogenated gene therapy construct, and methods for in vivo imaging of the same. Also provided are methods for non-invasive drug detection in a subject using a labeled antibody that recognizes a heterologous antigen conjugated to, encoded by, or otherwise associated with the drug.
(FR)L'invention porte sur un gène hybride obtenu par thérapie génique marqué par un halogène et comprenant des acides nucléiques marqués par un halogène, sur des procédés de préparation du gène hybride halogéné ainsi que sur des procédés d'imagerie <i>in vivo</i> dudit gène. Font également l'objet de cette invention des procédés de détection de médicaments chez un patient utilisant un anticorps marqué reconnaissant un antigène hétérologue conjugué à, codé par ou sinon associé audit médicament.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)