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1. (WO2003057840) COMPOSITIONS FOR DNA MEDIATED GENE SILENCING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/057840    International Application No.:    PCT/US2002/041642
Publication Date: 17.07.2003 International Filing Date: 26.12.2002
Chapter 2 Demand Filed:    23.07.2003    
IPC:
A61K 38/00 (2006.01), A61K 48/00 (2006.01), C12N 15/11 (2006.01)
Applicants: ALLELE BIOTECHNOLOGY & PHARMACEUTICALS, INC. [US/US]; 6827 Nancy Ridge Drive, San Diego, CA 92121-2233 (US)
Inventors: WANG, Jiwu; (US)
Agent: HAILE, Lisa, A.; Gray Cary Ware & Freidenrich LLP, 4365 Executive Drive, Suite 1100, San Diego, CA 92121-2133 (US)
Priority Data:
60/343,697 27.12.2001 US
10/202,479 23.07.2002 US
10/217,564 12.08.2002 US
Title (EN) COMPOSITIONS FOR DNA MEDIATED GENE SILENCING
(FR) COMPOSITIONS POUR SILENÇAGE GENIQUE REGULE PAR ADN
Abstract: front page image
(EN)DNA compositions that mediate gene silencing via RNA interference are provided. The DNA compositions include an RNA polymerase III promoter, which drives expression of a nucleotide sequence encoding an intermediate small interfering RNA molecule, and RNA polymerase III terminator.
(FR)L'invention concerne des compositions d'ADN qui régulent le silençage génique au moyen de l'interférence de l'ARN. Ces compositions d'ADN comprennent un promoteur de l'ARN polymérase III, qui entraîne l'expression d'une séquence nucléotidique codant une courte molécule d'ARN double brin (siRNA) intermédiaire, et un terminateur de l'ARN polymérase III.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)