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1. (WO2003057839) COMPOSITIONS AND METHODS RELATING TO URINARY SPECIFIC GENES AND PROTEINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/057839    International Application No.:    PCT/US2002/041613
Publication Date: 17.07.2003 International Filing Date: 23.12.2002
IPC:
C12Q 1/68 (2006.01)
Applicants: DIADEXUS, INC. [US/US]; 343 Oyster Point Boulevard, South San Francisco, CA 94080 (US) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NE, NL, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW only).
MACINA, Roberto, A. [AR/US]; (US) (For US Only).
SUN, Yongming [CN/US]; (US) (For US Only).
LIU, Chenghua [CN/US]; (US) (For US Only)
Inventors: MACINA, Roberto, A.; (US).
SUN, Yongming; (US).
LIU, Chenghua; (US)
Agent: LICATA, Jane, Massey; Licata & Tyrrel P.C., 66 E. Main Street, Marlton, NJ 08053 (US)
Priority Data:
60/343,690 28.12.2001 US
Title (EN) COMPOSITIONS AND METHODS RELATING TO URINARY SPECIFIC GENES AND PROTEINS
(FR) COMPOSITIONS ET PROCEDES SE RAPPORTANT A DES GENES ET DES PROTEINES SPECIFIQUES DE CELLULES URINAIRES
Abstract: front page image
(EN)The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic urinary cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating urinary cancer and non−cancerous disease states in urinary, identifying urinary tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered urinary tissue for treatment and research.
(FR)L'invention concerne des molécules d'acides nucléiques et des polypeptides identifiés présents dans des cellules urinaires normales et néoplasiques, y compris des fragments, des variants et des dérivés de ces acides nucléiques et polypeptides. Elle concerne aussi des anticorps dirigés contre ces polypeptides ainsi que des agonistes et des antagonistes de ces polypeptides. Elle concerne encore des compositions contenant les molécules d'acides nucléiques, les polypeptides, les anticorps, les agonistes et les antagoniste de l'invention et des procédés d'utilisation de ces compositions. Ces utilisations comprennent l'identification, le diagnostic, le suivi, la stadification, l'imagerie et le traitement de cancer de l'appareil urinaire et des états de maladie non cancéreuse des voies urinaires, l'identification de tissu urinaire, le suivi et l'identification et/ou la conception d'agonistes et d'antagonistes des polypeptides de l'invention. Les utilisations comprennent aussi la thérapie génique, la production d'animaux et de cellules transgéniques, et la production de tissu urinaire modifié génétiquement pour les traitements et la recherche.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)