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1. (WO2003057696) DEAZAPURINES AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/057696    International Application No.:    PCT/US2003/000366
Publication Date: 17.07.2003 International Filing Date: 07.01.2003
Chapter 2 Demand Filed:    25.07.2003    
IPC:
C07D 471/04 (2006.01)
Applicants: EISAI CO. LTD. [JP/JP]; 6-10 Koishikawa 4-Chome, Bunkyo-ku, Tokyo 112-8088 (JP) (For All Designated States Except US).
DAUN, Jane [US/US]; (US) (For US Only).
DAVIS, Heather, A. [CA/US]; (US) (For US Only).
GUSOVSKY, Fabian [US/US]; (US) (For US Only).
HISHINUMA, Ieharu [JP/JP]; (JP) (For US Only).
JIANG, Yimin [US/US]; (US) (For US Only).
KANEKO, Toshihiko [JP/JP]; (JP) (For US Only).
KIKUCHI, Kouichi [JP/JP]; (JP) (For US Only).
KOBAYASHI, Seiichi [JP/JP]; (US) (For US Only).
LESCARBEAU, Andre [CA/US]; (US) (For US Only).
LI, Xiang-Li [US/US]; (US) (For US Only).
MURAMOTO, Kenzo [JP/JP]; (JP) (For US Only).
OHI, Norihito [JP/JP]; (JP) (For US Only).
PESANT, Marc [CA/US]; (US) (For US Only).
SELETSKY, Boris, M. [RU/US]; (US) (For US Only).
SOEJIMA, Motohiko [JP/JP]; (JP) (For US Only).
YAO, Ye [CA/US]; (US) (For US Only).
YOKOHAMA, Hiromitsu [JP/JP]; (JP) (For US Only).
ZHAO, Janet, Y. [CN/US]; (US) (For US Only).
ZHENG, Wanjun [US/US]; (US) (For US Only).
TREMBLAY, Lynda [CA/US]; (US) (For US Only).
DE COSTA, Bruce [GB/US]; (US) (For US Only)
Inventors: DAUN, Jane; (US).
DAVIS, Heather, A.; (US).
GUSOVSKY, Fabian; (US).
HISHINUMA, Ieharu; (JP).
JIANG, Yimin; (US).
KANEKO, Toshihiko; (JP).
KIKUCHI, Kouichi; (JP).
KOBAYASHI, Seiichi; (US).
LESCARBEAU, Andre; (US).
LI, Xiang-Li; (US).
MURAMOTO, Kenzo; (JP).
OHI, Norihito; (JP).
PESANT, Marc; (US).
SELETSKY, Boris, M.; (US).
SOEJIMA, Motohiko; (JP).
YAO, Ye; (US).
YOKOHAMA, Hiromitsu; (JP).
ZHAO, Janet, Y.; (US).
ZHENG, Wanjun; (US).
TREMBLAY, Lynda; (US).
DE COSTA, Bruce; (US)
Agent: LAGNEAU, Nadège, M.; Choate, Hall & Stewart, Exchange Place, 53 State Street, Boston, MA 02109 (US)
Priority Data:
60/346,598 07.01.2002 US
Title (EN) DEAZAPURINES AND USES THEREOF
(FR) DEAZAPURINES ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention provides compounds having formula (I), wherein R1, R2, R3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.
(FR)L'invention concerne des composés de formule (I), dans laquelle R1, R2, R3 et n sont tels que décrits de façon générale et définis en classes et sous-classes dans la description. L'invention se rapporte en outre à des compositions pharmaceutiques de ces composés ainsi qu'à des procédés d'utilisation de ces composés pour traiter des troubles inflammatoires ou auto-immuns et prolifératifs, et en tant qu'inhibiteurs de l'expression des molécules d'adhésion cellulaire et de la transduction des signaux des cytokines inflammatoires d'une manière générale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)