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Machine translation
1. (WO2003057687) METHODS FOR PREPARING DOXORUBICIN DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/057687    International Application No.:    PCT/US2002/041604
Publication Date: 17.07.2003 International Filing Date: 23.12.2002
IPC:
C07H 15/203 (2006.01), C12P 19/56 (2006.01)
Applicants: ALBANY MOLECULAR RESEARCH, INC. [US/US]; 21 Corporate Circle Albany, NY 12203-2086 (US) (For All Designated States Except US).
THE UNIVERSITY OF IOWA RESEARCH FOUNDATION [US/US]; 214 Technology Innovation Center Iowa City, IA 52242-5000 (US) (For All Designated States Except US).
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street 12th floor Oakland, CA 94607-5200 (US) (For All Designated States Except US).
ALTREUTER, David, H. [US/US]; (US) (For US Only).
CLARK, Douglas, S. [US/US]; (US) (For US Only).
MICHELS, Peter, C. [US/US]; (US) (For US Only).
RICH, Joseph, O. [US/US]; (US) (For US Only).
MECKLER, Harold [US/US]; (US) (For US Only).
DORDICK, Jonathan, S. [US/US]; (US) (For US Only)
Inventors: ALTREUTER, David, H.; (US).
CLARK, Douglas, S.; (US).
MICHELS, Peter, C.; (US).
RICH, Joseph, O.; (US).
MECKLER, Harold; (US).
DORDICK, Jonathan, S.; (US)
Agent: GOLDMAN, Michael, L.; Nixon Peabody LLP Clinton Square P.O. Box 31051 Rochester, NY 14603-1051 (US)
Priority Data:
60/344,279 27.12.2001 US
Title (EN) METHODS FOR PREPARING DOXORUBICIN DERIVATIVES
(FR) PROCEDES PERMETTANT DE PREPARER DES DERIVES DE DOXORUBICINE
Abstract: front page image
(EN)The present invetion relates to a process for preparation of a product compound of formula (I), where R¿1? is an acyl group. The process involves reacting a starting compound of formula (II), with an activated acyl donor compound in the presence of a non-chemically modified lipase, under conditions effective to produce the product compound.
(FR)L'invention concerne un procédé de préparation d'un composé représenté par la formule (I), dans laquelle R¿1? représente un groupe acyle. Ce procédé consiste à faire réagir un composé de départ représenté par la formule (II) avec un donneur acyle activé en présence d'une lipase n'ayant pas été chimiquement modifiée, dans des conditions qui permettent d'obtenir efficacement le composé selon l'invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)