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1. (WO2003057666) INHIBITORS OF DIPEPTIDYL PEPTIDASE IV

Pub. No.:    WO/2003/057666    International Application No.:    PCT/US2002/041469
Publication Date: Jul 17, 2003 International Filing Date: Dec 26, 2002
IPC: A61K 38/00
C07D 205/04
C07D 207/04
C07D 207/16
C07D 207/20
C07D 207/22
C07D 209/42
C07D 209/46
C07D 209/48
C07D 217/14
C07D 217/16
C07D 217/26
C07D 263/06
C07D 277/04
C07D 277/06
C07D 295/125
C07D 295/185
C07D 401/06
C07D 401/12
C07D 403/04
C07D 403/06
C07D 409/06
C07D 417/06
C07K 5/078
C07K 5/097
Applicants: GUILFORD PHARMACEUTICALS
BELYAKOV, Sergei
HAMILTON, Gregory, S.
HURST, David, Chadwick
KALISH, Vincent, J.
LI, Weixing
WANG, Eric
WILKINSON, Douglas
WU, Yong-Qian
XU, Weizheng
Inventors: BELYAKOV, Sergei
HAMILTON, Gregory, S.
HURST, David, Chadwick
KALISH, Vincent, J.
LI, Weixing
WANG, Eric
WILKINSON, Douglas
WU, Yong-Qian
XU, Weizheng
Title: INHIBITORS OF DIPEPTIDYL PEPTIDASE IV
Abstract:
Novel inhibitors of dipeptidyl peptidase IV (DPP IV), pharmaceutical compositions comprising therapeutically effective amounts of novel inhibitors of DPP IV, and novel methods of treating medical conditions are provided. The novel inhibitors of DPP IV described herein are useful in the treatment of neurological disorders, diabetes, inflammatory disorders such as arthritis, obesity, osteoporosis, and of such other enumerated conditions as can be treated with inhibitors of DPP IV.