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1. (WO2003057250) CANCER TREATMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/057250    International Application No.:    PCT/GB2003/000105
Publication Date: 17.07.2003 International Filing Date: 13.01.2003
Chapter 2 Demand Filed:    24.07.2003    
A61K 31/337 (2006.01), A61K 51/10 (2006.01)
Applicants: ANTISOMA PLC [GB/GB]; West Africa House Hanger Lane Ealing London W5 3QR (GB) (For All Designated States Except US).
Inventors: ROWLINSON-BUSZA, Gail; (GB)
Agent: THOMAS, Philip, J., D.; Eric Potter Clarkson Park View House 58 The Ropewalk Nottingham NG1 5DD (GB)
Priority Data:
0200657.5 12.01.2002 GB
Abstract: front page image
(EN)The invention relates to a therapeutic system comprising (i) a radiolabelled antibody, which binds selectively to polymorphic epithelial mucin (PEM) such as the monoclonal antibody HMFG−1, and (ii) a chemotherapeutic agent, such as Taxotere ®. The radiolabelled antibody and chemotherapeutic agent are administered in combination with one another to produce a synergistic therapeutic effect.
(FR)L'invention se rapporte à un système thérapeutique comprenant (i) un anticorps radiomarqué, qui se fixe de manière sélective à une mucine épithéliale polymorphe (PEM) telle que l'anticorps monoclonal HMFG-1, et (ii) un agent chimiothérapeutique, tel qu'un Taxotere$m(3). Ledit anticorps radiomarqué et l'agent chimiothérapeutique sont administrés en combinaison l'un avec l'autre, afin de produire un effet thérapeutique synergique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)