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1. (WO2003057241) AGENTS PROMOTING THE PROLIFERATION AND/OR DIFFERENTIATION OF HEMATOPOIETIC STEM CELLS AND/OR HEMATOPOIETIC PRECURSOR CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/057241    International Application No.:    PCT/JP2002/013862
Publication Date: 17.07.2003 International Filing Date: 27.12.2002
IPC:
A61K 38/16 (2006.01), A61K 38/17 (2006.01), A61K 38/18 (2006.01), A61K 38/20 (2006.01)
Applicants: DAIICHI SUNTORY PHARMA CO., LTD. [JP/JP]; 5-7-2, Kojimachi, Chiyoda-ku, Tokyo 102-0083 (JP) (AT, AU, BE, BG, BR, CA, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IL, IT, KR, LU, MC, NL, PT, SE, SI, SK, TR only).
SUNTORY LIMITED [JP/JP]; 1-40, Dojimahama 2-chome, Kita-ku, Osaka-shi, Osaka 530-8203 (JP) (JP only).
DAIICHI SUNTORY BIOMEDICAL RESEARCH LTD. [JP/JP]; 1-1, Wakayamadai 1-chome, Shimamoto-cho, Mishima-gun, Osaka 618-8503 (JP) (For All Designated States Except US).
MIURA, Kenju [JP/JP]; (JP) (For US Only).
HARUYAMA, Munetada [JP/JP]; (JP) (For US Only).
KODAMA, Shiho [JP/JP]; (JP) (For US Only)
Inventors: MIURA, Kenju; (JP).
HARUYAMA, Munetada; (JP).
KODAMA, Shiho; (JP)
Agent: SHAMOTO, Ichio; YUASA AND HARA, Section 206, New Ohtemachi Bldg., 2-1, Ohtemachi 2-chome, Chiyoda-ku, Tokyo 100-0004 (JP)
Priority Data:
2001-400330 28.12.2001 JP
Title (EN) AGENTS PROMOTING THE PROLIFERATION AND/OR DIFFERENTIATION OF HEMATOPOIETIC STEM CELLS AND/OR HEMATOPOIETIC PRECURSOR CELLS
(FR) AGENTS FAVORISANT LA PROLIFERATION ET/OU LA DIFFERENCIATION DE CELLULES SOUCHES HEMATOPOIETIQUES ET/OU DE PRECURSEURS HEMATOPOIETIQUES
Abstract: front page image
(EN)It is intended to provide agents promoting the proliferation and/or differentiation of hematopoietic stem cells and/or hematopoietic precursor cells which are useful as remedies for diseases induced by the insufficient proliferation and/or differentiation of hematopoietic stem cells and/or hematopoietic precursor cells, in particular, diseases associated with a diffuse decrease in hematopoietic cells and/or hematopoietic hypofunction. The above problem is solved by providing agents for promoting the proliferation and/or differentiation of hematopoietic stem cells and/or hematopoietic precursor cells which contain as the active ingredient cofilin.
(FR)L'invention vise à créer des agents favorisant la prolifération et/ou la différenciation de cellules souches hématopoïétiques et/ou de précurseurs hématopoïétiques, utiles comme remèdes à des maladies induites par la prolifération et/ou la différenciation insuffisantes de cellules souches hématopoïétiques et/ou de précurseurs hématopoïétiques, en particulier des maladies associées à une diminution diffuse des cellules hématopoïétiques et/ou à une hypofonction hématopoïétique. A cet effet, les agents selon l'invention, favorisant la prolifération et/ou la différenciation de cellules souches hématopoïétiques et/ou de précurseurs hématopoïétiques, contiennent de la cofiline comme principe actif.
Designated States: AU, BR, CA, CN, IL, JP, KR, US.
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)