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1. (WO2003057194) STERILE FILTERED NANOPARTICULE FORMULATIONS OF BUDESONIDE AND BECLOMETHASONE HAVING TYLOXAPOL AS A SURFACE STABILIZER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/057194    International Application No.:    PCT/US2002/041768
Publication Date: 17.07.2003 International Filing Date: 31.12.2002
IPC:
A61K 9/00 (2006.01), A61K 9/14 (2006.01), A61K 31/573 (2006.01), A61K 31/58 (2006.01)
Applicants: ELAN PHARMA INTERNATIONAL LTD. [IE/IE]; Wil House Shannon Business Park Shannon County Clare (IE) (For All Designated States Except US).
BOSCH, H., William [US/US]; (US) (For US Only).
MARCERA, Donna, M. [US/US]; (US) (For US Only).
OSTRANDER, Kevin, D. [US/US]; (US) (For US Only).
RYDE, Niels, P. [SE/US]; (US) (For US Only).
WHITE, Douglas, A. [CA/US]; (US) (For US Only)
Inventors: BOSCH, H., William; (US).
MARCERA, Donna, M.; (US).
OSTRANDER, Kevin, D.; (US).
RYDE, Niels, P.; (US).
WHITE, Douglas, A.; (US)
Agent: SIMKIN, Michele, M.; Foley & Lardner Washington Harbour 3000 K Street, N.W., Suite 500 Washington, DC 20007-5143 (US)
Priority Data:
10/035,324 04.01.2002 US
Title (EN) STERILE FILTERED NANOPARTICULE FORMULATIONS OF BUDESONIDE AND BECLOMETHASONE HAVING TYLOXAPOL AS A SURFACE STABILIZER
(FR) FORMULATIONS NANOPARTICULAIRES FILTREES STERILES DE BUDESONIDE ET DE BECLOMETHASONE PRESENTANT DU TYLOXAPOL EN TANT QU'AGENT STABILISATEUR DE SURFACE
Abstract: front page image
(EN)The invention relates to sterile filtered nanoparticulate compositions of beclomethasone and/or budesonide having a surface stabilizer tyloxapol and, optionally, one or more secondary surface stabilizers absorbed onto the surfaces thereof. The nanoparticulate compositions have an optimal effective average particle size of less than about 150 nm.
(FR)L'invention concerne des compositions nanoparticulaires filtrées stériles de béclométhasone et/ou de budesonide présentant du tyloxapol en tant qu'agent stabilisateur de surface et, éventuellement, un ou plusieurs agents stabilisateurs de surface secondaires absorbés sur lesdites surfaces. Les compositions nanoparticulaires présentent une dimension particulaire moyenne efficace optimale inférieure à environ 150 nanomètres.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)