Search International and National Patent Collections
|1. (WO2003057007) SYSTEM FOR MONITORING BACTERIAL TUMOR TREATMENT|
|Inventors:||ZHAO, Ming, M.D., Ph.D.
LI, Xiao-Ming, M.D., Ph.D.
YANG, Meng, M.D., Ph.D.
XU, Mingxu, M.D.
JIANG, Ping, M.D.
LI, Linga, M.D.
|Title:||SYSTEM FOR MONITORING BACTERIAL TUMOR TREATMENT|
A method to follow the progress of tumor treatment in subjects utilizes bacteria that have been modified to express a fluorescent protein. The method can also monitor expression of genes associated with the bacteria that produce therapeutic agents during the course of treatment, optionally against a background of fluorescence generated by the tumor itself. The method permits visualization of the progress of treatment in live subjects so that treatments can be modified according to their efficacy.