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1. (WO2003057006) USE OF ANTIBODIES AGAINST THE MUC18 ANTIGEN

Pub. No.:    WO/2003/057006    International Application No.:    PCT/US2002/041582
Publication Date: Jul 17, 2003 International Filing Date: Dec 26, 2002
IPC: C07K 16/18
C07K 16/28
C07K 16/30
Applicants: ABGENIX, INC.
Inventors: GUDAS, Jean
BAR-ELI, Menashe
Title: USE OF ANTIBODIES AGAINST THE MUC18 ANTIGEN
Abstract:
The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the diagnosis and treatment of disorders associated with increased activity of MUC18, in particular, tumors, such as melanomas.