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Machine translation
1. (WO2003055442) TREATMENT OF SEPSIS BY LOW DOSE ADMINISTRATION OF TISSUE FACTOR PATHWAY INHIBITOR (TFPI)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/055442    International Application No.:    PCT/US2002/032625
Publication Date: 10.07.2003 International Filing Date: 15.10.2002
Chapter 2 Demand Filed:    14.05.2003    
IPC:
A61K 38/57 (2006.01)
Applicants: CHIRON CORPORATION [US/US]; 4560 Horton Street, Emeryville, CA 94608-2917 (US) (For All Designated States Except US).
CREASEY, Alba, A. [US/US]; (US) (For US Only)
Inventors: CREASEY, Alba, A.; (US)
Agent: GUTH, Joseph, H.; Chiron Corporation, 4560 Horton Street, Emeryville, CA 94608-2917 (US)
Priority Data:
60/328,806 15.10.2001 US
Title (EN) TREATMENT OF SEPSIS BY LOW DOSE ADMINISTRATION OF TISSUE FACTOR PATHWAY INHIBITOR (TFPI)
(FR) TRAITEMENT D'UNE MALADIE INFECTIEUSE PAR L'ADMINISTRATION D'UNE FAIBLE DOSE D'UN INHIBITEUR DE VOIE D'ACCES DE THROMBOPLASTINE TISSULAIRE (TFPI)
Abstract: front page image
(EN)Methods for prophylactically or therapeutically treating sepsis or septic shock involve administration of tissue factor pathway inhibitor (TFPI) or a TFPI analog to patients suffering from sepsis or other inflammatory conditions. The methods involve the use of continuous intravenous infusion of TFPI or a TFPI analog at low doses to avoid adverse side effects.
(FR)L'invention concerne des procédés de prévention ou de traitement d'une maladie infectieuse ou d'un choc septique comportant l'administration d'un inhibiteur de voie d'accès de thromboplastine tissulaire (TFPI) ou d'un analogue TFPI à des patients souffrant d'une maladie infectieuse ou d'autres états inflammatoires. Ces procédés recourent à l'utilisation d'une injection intraveineuse d'un TFPI ou d'un analogue TFPI à faibles doses pour éviter les effets secondaires fâcheux.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)