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Machine translation
1. (WO2003053136) TRIPLE TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/053136    International Application No.:    PCT/US2002/040929
Publication Date: 03.07.2003 International Filing Date: 20.12.2002
IPC:
C12N 15/85 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, 5th floor, Oakland, CA 94607-5200 (US) (For All Designated States Except US).
LAFERLA, Frank, M. [US/US]; (US) (For US Only)
Inventors: LAFERLA, Frank, M.; (US)
Agent: BONNER, Cynthia, A.; Christie, Parker & Hale LLP, Post Office Box 7068, Pasadena, CA 91109-7068 (US)
Priority Data:
60/343,383 20.12.2001 US
Title (EN) TRIPLE TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE
(FR) MODELE DE SOURIS TRIPLEMENT TRANSGENIQUE DE LA MALADIE D'ALZHEIMER
Abstract: front page image
(EN)The present invention relates to a triple transgenic animal model for Alzheimer's disease as well as to methods for generating multi-transgenic animals. The present invention also relates to methods for screening biologically active agents potentially useful for treating and/or ameliorating Alzheimer's disease (AD) or AD-type pathologies, compositions useful for treating AD or AD-type pathologies, and methods of treating AD patients.
(FR)La présente invention concerne un modèle d'animal triplement transgénique destiné à la maladie d'Alzheimer, ainsi que des méthodes de génération d'animaux multi-transgéniques. Cette invention a également trait à des méthodes de criblage d'agents actifs biologiquement utilisés de manière efficace dans le traitement et/ou l'amélioration de la maladie d'Alzheimer ou de pathologies du type de la maladie d'Alzheimer, à des compositions utilisés dans le traitement de la maladie d'Alzheimer ou de pathologies du type de la maladie d'Alzheimer, et à des méthodes de traitement de patients souffrant de la maladie d'Alzheimer.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)