Processing

Please wait...

Settings

Settings

Goto Application

1. WO2003043577 - MODULATORS OF RHO C ACTIVITY

Publication Number WO/2003/043577
Publication Date 30.05.2003
International Application No. PCT/US2002/037096
International Filing Date 19.11.2002
IPC
C07D 513/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
513Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/, C07D477/232
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
CPC
C07D 513/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
513Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • ICONIX PHARMACEUTICALS, INC. [US]/[US] (AllExceptUS)
  • SUN, Dongxu [CN]/[US] (UsOnly)
  • PERKINS, Edward, L. [US]/[CA] (UsOnly)
  • TUGENDREICH, Stuart [US]/[US] (UsOnly)
  • LEE, Ving, J. [US]/[US] (UsOnly)
Inventors
  • SUN, Dongxu
  • PERKINS, Edward, L.
  • TUGENDREICH, Stuart
  • LEE, Ving, J.
Agents
  • ROBINS, Roberta, L.
Priority Data
60/331,75619.11.2001US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) MODULATORS OF RHO C ACTIVITY
(FR) MODULATEURS DE L'ACTIVITE DE RHO C
Abstract
(EN) Compounds of formula (1) modulate the activity of Rho C, wherein n is 2 to 5, inclusive; R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently halo, lower alkyl, lower alkoxy, lower alkylamino, trifluoromethyl, nitro, lower alkylthio, or two adjacent residues form cycloalkyl, cycloalkenyl, aryl, or lower alkylenedioxy; and pharmaceutically acceptable salts thereof.
(FR) L'invention concerne des composés de formule générale (1) qui modulent l'activité de Rho C, dans laquelle n est compris entre 2 et 5, inclus; R1, R2, R3, R4, R5, R6, R7, R8, et R9 représentent indépendamment les uns des autres halo, alkyle inférieur, alcoxy inférieur, alkylamino inférieur, trifluorométhyle, nitro, alkylthio inférieur, ou deux résidus adjacents formant cycloalkyle, cycloalkényle, aryle, ou alkylènedioxy inférieur; et des sels pharmaceutiquement acceptables de ceux-ci.
Related patent documents
Latest bibliographic data on file with the International Bureau