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1. (WO2003012406) METHODS AND SYSTEMS FOR MICROFLUIDIC PROCESSING
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2003/012406 International Application No.: PCT/US2002/009440
Publication Date: 13.02.2003 International Filing Date: 27.03.2002
Chapter 2 Demand Filed: 24.02.2003
IPC:
B01L 3/00 (2006.01) ,B81B 1/00 (2006.01) ,F04B 19/00 (2006.01) ,F04B 19/24 (2006.01) ,F04F 1/06 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
L
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3
Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
B PERFORMING OPERATIONS; TRANSPORTING
81
MICRO-STRUCTURAL TECHNOLOGY
B
MICRO-STRUCTURAL DEVICES OR SYSTEMS, e.g. MICRO-MECHANICAL DEVICES
1
Devices without movable or flexible elements, e.g. micro-capillary devices
F MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
04
POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
B
POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
19
Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/-F04B17/158
F MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
04
POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
B
POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
19
Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/-F04B17/158
20
Other positive-displacement pumps
24
Pumping by heat expansion of pumped fluid
F MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
04
POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
F
PUMPING OF FLUID BY DIRECT CONTACT OF ANOTHER FLUID OR BY USING INERTIA OF FLUID TO BE PUMPED; SIPHONS
1
Pumps using positively or negatively pressurised fluid medium acting directly on the liquid to be pumped
06
the fluid medium acting on the surface of the liquid to be pumped
Applicants:
HANDYLAB, INC. [US/US]; 3310 Plymouth Road Suite 400 Ann Arbor, MI 48105, US
Inventors:
PARUNAK, Gene; US
HANDIQUE, Kalyan; US
WU, Betty; US
GANESAN, Karthik; US
Agent:
BARKER, Bruce, J. ; Pennie & Edmonds LLP 1155 Avenue of the Americas New York, NY 10036, US
Priority Data:
10/014,51914.12.2001US
10/014,52014.12.2001US
10/075,37115.02.2002US
60/307,63826.07.2001US
Title (EN) METHODS AND SYSTEMS FOR MICROFLUIDIC PROCESSING
(FR) PROCEDES ET SYSTEMES DE TRAITEMENT MICROFLUIDIQUE
Abstract:
(EN) The present invention relates to a system and method for moving samples, such as fluids, within a microfluidic system using a plurality of gas actuators (168, 170, 172) for applying pressure at different locations within the microfluidic. The system includes a substrate (130, 132) which forms a fluid network through which fluid flows, and a plurality of gas actuators (168, 170, 172) integral with the substrate (130, 132). One such actuator (168) is coupled to the network at a first location for providing gas pressure to move a microfluidic sample within the network. Another gas actuator (170) is coupled to the network at a second location for providing gas pressure to further move at least a portion of the microfluidic sample within the network. A valve (915, 216) is coupled to the microfluidic network so that, when the valve is closed, it substantially isolates the second gas actuator from the first gas actuator.
(FR) La présente invention concerne un système et un procédé destinés à déplacer des échantillons, tels que des fluides, dans un système microfluidique faisant intervenir une pluralité d'actionneurs à gaz (168, 170, 172) permettant d'appliquer une pression au niveau de plusieurs emplacements à l'intérieur de ce système microfluidique. Ledit système comprend un substrat (130, 132) formant un réseau fluidique à travers lequel s'écoule un fluide, ainsi qu'une pluralité d'actionneurs à gaz (168, 170, 172) formés de manière intégrée avec le substrat (130, 132). Un actionneur (168) est couplé au réseau au niveau d'un premier emplacement de façon à produire une pression de gaz impliquant le déplacement d'un échantillon microfluidique à l'intérieur du réseau. Un autre actionneur (170) est couplé au réseau au niveau d'un second emplacement de manière à produire une pression de gaz impliquant le déplacement d'une partie au moins de l'échantillon microfluidique à l'intérieur dudit réseau. Une valve (915, 216) est couplée au réseau microfluidique de manière que la fermeture de cette valve isole sensiblement le second actionneur à gaz du premier actionneur à gaz.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)