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Machine translation
1. (WO2003008552) MLL TRANSLOCATIONS SPECIFY A DISTINCT GENE EXPRESSION PROFILE, DISTINGUISHING A UNIQUE LEUKEMIA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/008552    International Application No.:    PCT/US2002/022823
Publication Date: 30.01.2003 International Filing Date: 17.07.2002
Chapter 2 Demand Filed:    06.02.2003    
IPC:
C12Q 1/68 (2006.01)
Applicants: WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH [US/US]; Nine Cambridge Center, Cambridge, MA 02142 (US) (For All Designated States Except US).
DANA-FARBER CANCER INSTITUTE, INC. [US/US]; 44 Binney Street, Boston, MA 02115 (US) (For All Designated States Except US).
GOLUB, Todd, R. [US/US]; (US) (For US Only).
ARMSTRONG, Scott, A. [US/US]; (US) (For US Only).
KORSMEYER, Stanley, J. [US/US]; (US) (For US Only)
Inventors: GOLUB, Todd, R.; (US).
ARMSTRONG, Scott, A.; (US).
KORSMEYER, Stanley, J.; (US)
Agent: TREANNIE, Lisa, M.; Hamilton, Brook, Smith & Reynolds, P.C., 530 Virginia Road, P.O. Box 9133, Concord, MA 01742-9133 (US)
Priority Data:
60/306,103 17.07.2001 US
Title (EN) MLL TRANSLOCATIONS SPECIFY A DISTINCT GENE EXPRESSION PROFILE, DISTINGUISHING A UNIQUE LEUKEMIA
(FR) TRANSLOCATIONS DE MLL INDIQUANT UN PROFIL D'EXPRESSION GENIQUE DISTINCT QUI PERMET DE DISTINGUER UNE LEUCEMIE UNIQUE
Abstract: front page image
(EN)The present invention relates to the diagnosis of mixed lineage leukemia (MLL), acute lymphoblastic leukemia (ALL), and acute myellgenous leukemia (AML) according to the gene expression profile of a sample from an individual, as well as to methods of therapy and screening that utilize the genes indentified herein as targets.
(FR)L'invention concerne des méthodes permettant de diagnostiquer la leucémie à lignée mixte (MLL), la leucémie lymphoblastique aiguë (ALL) et la leucémie myélogène aiguë (AML), en fonction du profil de l'expression génique d'un échantillon provenant d'un individu. L'invention concerne également des méthodes de traitement et de criblage utilisant les gènes identifiés comme cibles.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)