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1. WO2003008450 - TUMOR ANTIGEN

Publication Number WO/2003/008450
Publication Date 30.01.2003
International Application No. PCT/JP2002/005799
International Filing Date 11.06.2002
Chapter 2 Demand Filed 10.12.2002
IPC
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
C07K 14/47 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
G01N 33/574 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
CPC
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 13/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
08of the prostate
A61P 13/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
A61P 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
Applicants
  • ITOH, Kyogo [JP]/[JP]
  • SHICHIJO, Shigeki [JP]/[JP] (UsOnly)
Inventors
  • ITOH, Kyogo
  • SHICHIJO, Shigeki
Agents
  • SHOJI, Takashi
Priority Data
2001-17705812.06.2001JP
2001-25072821.08.2001JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) TUMOR ANTIGEN
(FR) ANTIGENES TUMORAUX
Abstract
(EN) A gene encoding a tumor antigen which is recognized by HLA−A2−restricted cytotoxic T lymphocytes (CTL) and/or capable of inducing CTL is identified from a human colorectal caner cell line and a human esophageal cancer cell line. Further, a peptide having the epitope of the above tumor antigen is found out. Moreover, a polypeptide encoded by the above gene or the above−described peptide, a polynucleotide encoding one of them or its complementary strand, a recombinant vector, a transformant, etc. are provided.
(FR) L'invention concerne un gène codant pour un antigène tumoral reconnu par des lymphocytes cytotoxiques T (CTL) à restriction HLA-A2 et/ou capable d'induire CTL, qui est identifié par des lignées cellulaires du cancer colorectal humain et du cancer oesophagien humain. L'invention concerne également un peptide comprenant un épitope de l'antigène précité. En outre, l'invention concerne un polypeptide codé par le gène ou le peptide précité, un polynucléotide codant pour l'un d'eux ou son brin complémentaire, un vecteur de recombinaison, et transformant, etc.
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