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Machine translation
1. (WO2003007686) USE OF COPPER CHELATORS TO INHIBIT THE INACTIVATION OF PROTEIN C
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2003/007686 International Application No.: PCT/US2002/022951
Publication Date: 30.01.2003 International Filing Date: 19.07.2002
Chapter 2 Demand Filed: 05.02.2003
IPC:
A61K 38/00 (2006.01) ,A61K 38/48 (2006.01) ,C07K 5/02 (2006.01) ,C07K 5/06 (2006.01) ,C07K 5/083 (2006.01) ,C07K 5/103 (2006.01) ,C07K 5/113 (2006.01) ,C07K 7/06 (2006.01)
Applicants: DMI BIOSCIENCES, INC.[US/US]; 3601 S. Clarkson Street #420 Englewood, CO 80110-3948, US
Inventors: BAR-OR, David; US
YUKL, Richard, L.; US
Agent: CONNELL, Gary, J. ; Sheridan Ross P.C. Suite 1200 1560 Broadway Denver, CO 80202-5141, US
Priority Data:
60/307,00519.07.2001US
60/344,51428.12.2001US
Title (EN) USE OF COPPER CHELATORS TO INHIBIT THE INACTIVATION OF PROTEIN C
(FR) UTILISATION DE CHELATEURS DE CUIVRE POUR INHIBER L'INACTIVATION DE LA PROTEINE C
Abstract: front page image
(EN) The present invention is based on the unexpected discovery that activated protein C (APC) is inactivated by copper. Accordingly, the invention provides improved methods of treating diseases and conditions treatable with APC which utilize a copper chelator to inhibit the inactivation of APC by copper.
(FR) La présente invention est basée sur la découverte inattendue que la protéine C activée (APC) est inactivée par le cuivre. Par conséquent, l'invention concerne des procédés améliorés de traitement de maladies et d'états pouvant être traités par l'APC, lesquelles utilisent un chélateur de cuivre pour inhiber l'inactivation de l'APC par le cuivre.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)