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1. (WO2003006624) 47619 AND 47621, HUMAN ION CHANNELS, AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/006624    International Application No.:    PCT/US2002/022301
Publication Date: 23.01.2003 International Filing Date: 10.07.2002
IPC:
C12N 15/00 (2006.01), C12N 15/12 (2006.01), C12N 15/63 (2006.01)
Applicants: MILLENNIUM PHARMACEUTICAL, INC. [US/US]; 75 Sidney Street Cambridge, MA 02139 (US) (For All Designated States Except US).
CURTIS, Rory, A., J. [GB/US]; (US) (For US Only)
Inventors: CURTIS, Rory, A., J.; (US)
Agent: SILVERI, Jean, M.; Millennium Pharmaceuticals, Inc., 75 Sidney Street, Cambridge, MA 02139 (US)
Priority Data:
60/304,257 10.07.2001 US
Title (EN) 47619 AND 47621, HUMAN ION CHANNELS, AND USES THEREOF
(FR) MOLECULES 47619 ET 47621, CANAUX IONIQUES HUMAINS ET UTILISATIONS DE CES MOLECULES
Abstract: front page image
(EN)The invention provides isolated nucleic acid molecules, designated 47619 and 47621 nucleic acid molecules, which encode novel 47619 and 47621-related ion channel molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 47619 and 47621 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an 47619 and 47621 gene has been introduced or disrupted. The invention still further provides isolated 47619 and 47621 proteins, fusion proteins, antigenic peptides and anti-47619 and 47621 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
(FR)La présente invention concerne des molécules d'acide nucléique isolées, appelée molécules d'acide nucléique 47619 et 47621, codantes pour des molécules de canaux ioniques associées à ces nouvelles molécules. Cette invention concerne aussi des molécules d'acide nucléique antisens, des vecteurs d'expression de recombinaison contenant ces molécules d'acide nucléique 47619 et 47621, des cellules hôtes dans lesquelles ces vecteurs d'expression ont été introduits et des animaux transgéniques dans lesquels un gène 47619 et 47621 a été introduit ou interrompu. Cette invention concerne encore des protéines 47619 et 47621, des protéines de fusion, des peptides antigéniques et des anticorps anti 47619 et anti 47621. Cette invention concerne enfin des techniques diagnostiques utilisant ces compositions..
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)