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Machine translation
1. (WO2003006615) METHOD OF MAKING FGF-12 AND KGF-2
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2003/006615 International Application No.: PCT/US2002/021823
Publication Date: 23.01.2003 International Filing Date: 12.07.2002
Chapter 2 Demand Filed: 06.02.2003
IPC:
C12N 1/21 (2006.01) ,C12N 15/12 (2006.01) ,C12N 15/70 (2006.01)
Applicants: LAIRD, Michael, W.[US/US]; US (UsOnly)
HUMAN GENOME SCIENCES, INC.[US/US]; 9410 Key West Avenue Rockville, MD 20850, US (AllExceptUS)
Inventors: LAIRD, Michael, W.; US
Agent: WALES, Michele, M.; Human Genome Sciences, Inc. 9410 Key West Avenue Rockville, MD 20850, US
Priority Data:
60/304,64212.07.2001US
Title (EN) METHOD OF MAKING FGF-12 AND KGF-2
(FR) PROCEDE DE FABRICATION DE FGF-12 ET KGF-2
Abstract:
(EN) The present invention is directed to a method of expressing KGF-2 polypeptides in an ompT-deficient prokaryotic host cell. Also provided are ompT-deficient prokaryotic host cells comprising polynucleotides encoding KGF-2. The present invention is further directed to a method of expressing FGF-12 in an ompT-deficient prokaryotic host cell. Also provided are ompT-deficient prokaryotic host cells comprising polynucleotides encoding FGF-12.
(FR) La présente invention concerne un procédé permettant l'expression des polypeptides du facteur de croissance des kératinocytes KGF-2 dans une cellule hôte procaryote à déficience d'ompT. L'invention concerne également des cellules hôtes procaryotes à déficience d'ompT comprenant des polynucléotides codant le facteur KGF-2. L'invention concerne aussi un procédé permettant l'expression des polypeptides du facteur de croissance des fibroblastes FGF-12 dans une cellule hôte procaryote à déficience d'ompT. L'invention concerne enfin des cellules hôtes procaryotes à déficience d'ompT comprenant des polynucléotides codant le facteur FGF-12.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)