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1. (WO2003004635) NOVEL AMINOPEPTIDASE DERIVED FROM BACILLUS LICHENIFORMIS, GENE ENCODING THE AMINOPEPTIDASE, EXPRESSION VECTOR CONTAINING THE GENE, TRANSFORMANT AND METHOD FOR PREPARATION THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/004635    International Application No.:    PCT/KR2002/001280
Publication Date: 16.01.2003 International Filing Date: 06.07.2002
Chapter 2 Demand Filed:    06.01.2003    
IPC:
C12N 9/48 (2006.01), C12N 9/56 (2006.01)
Applicants: LG Life Sciences Ltd. [KR/KR]; 20, Yeoido-dong, Youngdeungpo-ku, Seoul 150-721 (KR) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NE, NL, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW only).
LEE, Young-Phil [KR/KR]; (KR) (For US Only).
LEE, Seung-won [KR/KR]; (KR) (For US Only).
JUNG, Chul-ho [KR/KR]; (KR) (For US Only).
KIM, Hyung-Cheol [KR/KR]; (KR) (For US Only).
CHOI, Soon-Yong [KR/KR]; (KR) (For US Only).
KIM, Jin-suk [KR/KR]; (KR) (For US Only).
KIM, Hyun-Sik [KR/KR]; (KR) (For US Only).
SEO, Jung-Woo [KR/KR]; (KR) (For US Only)
Inventors: LEE, Young-Phil; (KR).
LEE, Seung-won; (KR).
JUNG, Chul-ho; (KR).
KIM, Hyung-Cheol; (KR).
CHOI, Soon-Yong; (KR).
KIM, Jin-suk; (KR).
KIM, Hyun-Sik; (KR).
SEO, Jung-Woo; (KR)
Agent: CHO, In-jae; Newkorea International Patent & Law Office, 3rd Fl., Janghyun Bldg. 637-23, Yeoksam-dong, Gangnam-gu, Seoul 135-909 (KR)
Priority Data:
2001-0040268 06.07.2001 KR
2002-0030798 31.05.2002 KR
Title (EN) NOVEL AMINOPEPTIDASE DERIVED FROM BACILLUS LICHENIFORMIS, GENE ENCODING THE AMINOPEPTIDASE, EXPRESSION VECTOR CONTAINING THE GENE, TRANSFORMANT AND METHOD FOR PREPARATION THEREOF
(FR) AMINOPEPTIDASE DERIVEE DU BACILLUS LICHENIFORMIS, GENE CODANT LADITE AMINOPEPTIDASE, VECTEUR D'EXPRESSION CONTENANT LEDIT GENE, TRANSFORMANT ET METHODE DE PREPARATION ASSOCIEE
Abstract: front page image
(EN)The present invention relates to novel aminopeptidase derived from Bacillus licheniformis, a gene encoding the aminopeptidase, an expression vector containing the gene, a cell transformant transfected with the expression vector and a process for preparing a natural type protein using thereof. More particularly, the present invention relates to a gene encoding aminopeptidase which is cloned and manufactured using the recombinant DNA technique, an expression vector containing the gene, a cell transformant transfected with the expression vector and a recombinant aminopeptidase which is necessary to produce recombinant human growth hormone in a natural type protein and can be expressed in a high yield more stably and advantageously, compared with conventional methods for the purification.
(FR)La présente invention concerne une aminopeptidase dérivée du Bacillus licheniformis, un gène codant l'aminopeptidase, un vecteur d'expression contenant ledit gène, un transformant cellulaire transfecté à l'aide du vecteur d'expression et un procédé de préparation d'une protéine de type naturel faisant appel à ce dernier. La présente invention concerne notamment un gène codant l'aminopeptidase qui est clonée et fabriquée à l'aide de la technique de recombinaison de l'ADN, un vecteur d'expression contenant ledit gène, un transformant cellulaire transfecté par le vecteur d'expression et une aminopeptidase de recombinaison qui est nécessaire pour produire de l'hormone de croissance humaine de recombinaison dans une protéine de type naturel et qui peut être exprimée avec un rendement élevé de manière plus stable et plus avantageuse, comparé aux méthodes classiques de purification.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)