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1. (WO2003004007) USE OF TYROSINE KINASE INHIBITORS FOR TREATING INFLAMMATORY BOWEL DISEASES (IBD)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/004007    International Application No.:    PCT/IB2002/003317
Publication Date: 16.01.2003 International Filing Date: 28.06.2002
IPC:
A61K 31/00 (2006.01), A61K 31/015 (2006.01), A61K 31/095 (2006.01), A61K 31/40 (2006.01), A61K 31/403 (2006.01), A61K 31/404 (2006.01), A61K 31/415 (2006.01), A61K 31/4709 (2006.01), A61K 31/495 (2006.01), A61K 31/498 (2006.01), A61K 31/50 (2006.01), A61K 31/505 (2006.01), A61K 31/506 (2006.01), A61K 31/517 (2006.01), A61K 31/519 (2006.01), A61K 31/66 (2006.01), A61K 45/06 (2006.01)
Applicants: AB SCIENCE [FR/FR]; 3, avenue George V, F-75008 Paris (FR) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NE, NL, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW only).
MOUSSY, Alain [FR/FR]; (FR) (For US Only).
KINET, Jean-Pierre [FR/US]; (US) (For US Only)
Inventors: MOUSSY, Alain; (FR).
KINET, Jean-Pierre; (US)
Agent: MARTIN, Jean-Jacques; Cabinet Regimbeau, 20, rue de Chazelles, F-75847 Paris Cedex 17 (FR)
Priority Data:
60/301,405 29.06.2001 US
Title (EN) USE OF TYROSINE KINASE INHIBITORS FOR TREATING INFLAMMATORY BOWEL DISEASES (IBD)
(FR) UTILISATION D'INHIBITEURS DE TYROSINE KINASES POUR TRAITER LES MALADIES INTESTINALES INFLAMMATOIRES (MII)
Abstract: front page image
(EN)The present invention relates to a method for treating inflammatory bowel diseases (IBD), such as crohn's disease, comprising administering a tyrosine kinase inhibitor to a human in need of such treatment, more particularly a non-toxic, selective and potent c-kit inhibitor. Preferably, said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.
(FR)La présente invention concerne une méthode de traitement des maladies intestinales inflammatoires (MII), telles que la maladie de Crohn, qui consiste à administrer, à un patient humain nécessitant un tel traitement, un inhibiteur de tyrosine kinase et plus spécifiquement un inhibiteur c-kit non toxique, sélectif et puissant. De préférence, ledit inhibiteur est incapable de favoriser la mort de cellules dépendant de IL-3 cultivées en présence de IL-3.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)