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1. (WO2003004006) USE OF POTENT, SELECTIVE AND NON TOXIC C-KIT INHIBITORS FOR TREATING TUMOR ANGIOGENESIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/004006    International Application No.:    PCT/IB2002/003295
Publication Date: 16.01.2003 International Filing Date: 28.06.2002
IPC:
A61K 31/00 (2006.01), A61K 31/015 (2006.01), A61K 31/095 (2006.01), A61K 31/40 (2006.01), A61K 31/403 (2006.01), A61K 31/404 (2006.01), A61K 31/415 (2006.01), A61K 31/4709 (2006.01), A61K 31/498 (2006.01), A61K 31/505 (2006.01), A61K 31/506 (2006.01), A61K 31/517 (2006.01), A61K 31/519 (2006.01), A61K 45/06 (2006.01), G01N 33/50 (2006.01)
Applicants: AB SCIENCE [FR/FR]; 3, avenue George V, F-75008 Paris (FR) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NE, NL, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW only).
MOUSSY, Alain [FR/FR]; (FR) (For US Only).
KINET, Jean-Pierre [FR/US]; (US) (For US Only)
Inventors: MOUSSY, Alain; (FR).
KINET, Jean-Pierre; (US)
Agent: MARTIN, Jean-Jacques; Cabinet Régimbeau, 20, rue de Chazelles, F-75847 Paris Cedex 17 (FR)
Priority Data:
60/301,407 29.06.2001 US
Title (EN) USE OF POTENT, SELECTIVE AND NON TOXIC C-KIT INHIBITORS FOR TREATING TUMOR ANGIOGENESIS
(FR) UTILISATION D'INHIBITEURS DE MATERIEL C, PUISSANTS, SELECTIFS ET NON TOXIQUES POUR TRAITER L'ANGIOGENESE TUMORALE
Abstract: front page image
(EN)The present invention relates to a method for inhibiting tumor angiogenesis comprising administering a c-kit inhibitor to a human in need of such treatment, more particularly a non toxic, potent and selective c-kit inhibitor, wherein said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.
(FR)La présente invention concerne une méthode d'inhibition de l'angiogénèse tumorale consistant à administrer un inhibiteur de matériel c chez un humain nécessitant un tel traitement, notamment un inhibiteur de matériel c, sélectif, puissant et non toxique, ledit inhibiteur étant incapable de favoriser la mort de cellules dépendantes de l'IL-3 cultivées en présence d'IL-3.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)