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1. WO2003003007 - METHODS AND COMPOSITIONS USEFUL FOR THE PREDICTION OF BLOOD-BRAIN BARRIER PERMEATION

Publication Number WO/2003/003007
Publication Date 09.01.2003
International Application No. PCT/US2002/019736
International Filing Date 20.06.2002
Chapter 2 Demand Filed 15.01.2003
IPC
G01N 33/92 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
92involving lipids, e.g. cholesterol
CPC
G01N 33/92
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
92involving lipids, e.g. cholesterol ; , lipoproteins, or their receptors
Applicants
  • WYETH [US]/[US]
Inventors
  • DI, Li
  • KERNS, Edward, Harvel
Agents
  • CALNAN, William, H.
  • WILEMAN, David, F.
Priority Data
60/302,08529.06.2001US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS USEFUL FOR THE PREDICTION OF BLOOD-BRAIN BARRIER PERMEATION
(FR) METHODES ET COMPOSITIONS UTILES POUR PREDIRE LA PERMEABILITE DE LA BARRIERE HEMATO-ENCEPHALIQUE
Abstract
(EN) The present invention provides a method for the $i(in vitro) determination of the ability of a compound or a mixture of compounds to permeate the blood-brain barrier and a membrane composition useful therefor.
(FR) La présente invention concerne une méthode qui permet de déterminer $i(in vitro) la capacité d'un composé ou d'un mélange de composés à traverser la barrière hémato-encéphalique et une composition de membrane utile correspondante.
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