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1. (WO2003002745) THE CAGE GENE OF ACTINOBACILLUS ACTINOMYCETEMCOMITANS, THE PROTEIN IT ENCODES AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2003/002745 International Application No.: PCT/CA2002/000963
Publication Date: 09.01.2003 International Filing Date: 27.06.2002
Chapter 2 Demand Filed: 20.01.2003
IPC:
A61K 38/00 (2006.01) ,A61K 39/00 (2006.01) ,A61K 48/00 (2006.01) ,C07K 14/36 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
36
from Actinomyces; from Streptomyces (G)
Applicants: TENG, Yen-Tung, A.[CA/CA]; CA (UsOnly)
UNIVERSITY OF WESTERN ONTARIO[CA/CA]; Office of Industry Liaison Stevenson-Lawson Building Room 319 London, Ontario N6A 5B8, CA (AllExceptUS)
Inventors: TENG, Yen-Tung, A.; CA
Agent: BERESKIN & PARR; 40 King Street West 40th Floor Toronto, Ontario M5H 3Y2, CA
Priority Data:
60/301,17128.06.2001US
60/363,18911.03.2002US
Title (EN) THE CAGE GENE OF ACTINOBACILLUS ACTINOMYCETEMCOMITANS, THE PROTEIN IT ENCODES AND USES THEREOF
(FR) GENE CAGE D'ACTINOBACILLUS ACTINOMYCENTEMCOMITANS, PROTEINE CODEE PAR CE GENE ET UTILISATIONS DE LADITE PROTEINE
Abstract:
(EN) A gene and protein isolated from A. actinomycetemcomitans is described. The protein, designated CagE, can induce apoptosis and cell adhesion. The invention includes all diagnostic and therapeutic uses of the protein and antibodies to the protein.
(FR) La présente invention se rapporte à un nouveau gène isolé à partir de A. actinomycentemcomitans ainsi qu'à la protéine codée par ce gène. Cette protéine, appelée CagE, peut induire l'apoptose et l'adhésion cellulaire. Cette invention se rapporte également à toutes les utilisations diagnostiques et thérapeutiques de cette protéine et des anticorps dirigés contre cette protéine.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)