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1. (WO2003000856) IN VITRO PROTEIN INTERACTION DETECTION SYSTEMS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/000856    International Application No.:    PCT/US2002/019937
Publication Date: 03.01.2003 International Filing Date: 20.06.2002
IPC:
C12Q 1/68 (2006.01)
Applicants: PHYLOS, INC. [US/US]; 128 Spring Street Lexington, MA 02421 (US) (For All Designated States Except US).
KURZ, Markus [DE/US]; (US) (For US Only).
LOHSE, Peter [US/US]; (US) (For US Only)
Inventors: KURZ, Markus; (US).
LOHSE, Peter; (US)
Agent: ELBING, Karen, L.; Clark & Elbing LLP 101 Federal Street Boston, MA 02110 (US)
Priority Data:
60/300,267 21.06.2001 US
Title (EN) IN VITRO PROTEIN INTERACTION DETECTION SYSTEMS
(FR) SYSTEMES DE DETECTION D'INTERACTIONS PROTEIQUES IN VITRO
Abstract: front page image
(EN)Disclosed herein are DNA-protein fusion molecules and their use in in vitro assays for the identification of interactions between proteins or other molecules, the identification of transcriptional activator proteins, and the detection of compounds that inhibit protein/protein or protein/compound interactions. Also disclosed herein are the use of such DNA-protein fusion molecules in in vitro assays for the selection of interacting proteins and transcriptional activator proteins out of libraries.
(FR)L'invention concerne des molécules de fusion ADN-protéine et leur utilisation dans des analyses in vitro pour l'identification d'interactions entre des protéines ou d'autres molécules, pour l'identification de protéines activatrices de la transcription et pour la détection de composés inhibant les interactions protéine-protéine ou protéine-composé. L'invention concerne également l'utilisation de ces molécules de fusion ADN-protéine dans des analyses in vitro pour la sélection de protéines d'interaction et de protéines activatrices de la transcription à l'extérieur des bibliothèques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)