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1. (WO2003000707) ANTISENSE MODULATION OF SUPEROXIDE DISMUTASE 1, SOLUBLE EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2003/000707 International Application No.: PCT/US2002/019664
Publication Date: 03.01.2003 International Filing Date: 19.06.2002
Chapter 2 Demand Filed: 17.01.2003
IPC:
A61K 38/00 (2006.01) ,C12N 15/11 (2006.01)
Applicants: BENNETT, C. Frank[US/US]; US (UsOnly)
DOBIE, Kenneth[US/US]; US (UsOnly)
ISIS PHARMACEUTICALS, INC.[US/US]; 2292 Faraday Avenue Carlsbad, CA 92008, US (AllExceptUS)
Inventors: BENNETT, C. Frank; US
DOBIE, Kenneth; US
Agent: LICATA, Jane, Massey ; Licata & Tyrrell P.C. 66 E. Main Street Marlton, NJ 08053, US
Priority Data:
09/888,36021.06.2001US
Title (EN) ANTISENSE MODULATION OF SUPEROXIDE DISMUTASE 1, SOLUBLE EXPRESSION
(FR) MODULATION ANTI-SENS DE L'EXPRESSION DE LA SUPEROXYDE DISMUTASE 1 SOLUBLE
Abstract:
(EN) Antisense compounds, compositions and methods are provided for modulating the expression of superoxide dismutase 1, soluble. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding superoxide dismutase 1, soluble. Methods of using these compounds for modulation of superoxyde dismutase 1, soluble expression and for treatment of diseases associated with expression of superoxide dismutase 1, soluble are provided.
(FR) L'invention concerne des composés anti-sens, des compositions et des procédés associés permettant de moduler l'expression de la superoxyde dismutase 1 soluble. Les compositions renferment des composés anti-sens, notamment des oligonucléotides anti-sens, ciblés sur des acides nucléiques codant la superoxyde dismutase 1 soluble. L'invention concerne également des procédés d'utilisation de ces composés aux fins de modulation de l'expression de la superoxyde dismutase 1 soluble et de traitement de maladies associées avec l'expression de la superoxyde dismutase 1 soluble.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)