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Machine translation
1. (WO2003000283) METHODS OF INDUCING A CYTOTOXIC IMMUNE RESPONSE AND RECOMBINANT SIMIAN ADENOVIRUS COMPOSITIONS USEFUL THEREIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/000283    International Application No.:    PCT/US2002/015239
Publication Date: 03.01.2003 International Filing Date: 13.05.2002
Chapter 2 Demand Filed:    15.01.2003    
IPC:
A61K 39/00 (2006.01), A61K 39/235 (2006.01), A61K 48/00 (2006.01), C07K 14/025 (2006.01), C07K 14/08 (2006.01), C07K 14/145 (2006.01), C07K 14/16 (2006.01), C12N 7/04 (2006.01), C12N 15/861 (2006.01)
Applicants: THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY [US/US]; 3601 Spruce Street Philadelphia, PA 19104 (US) (For All Designated States Except US).
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; 3160 Chestnut Street, Suite 200, Philadelphia, PA 19104 (US) (For All Designated States Except US).
ERTL, Hildegund, C., J. [DE/US]; (US) (For US Only).
WILSON, James, M. [US/US]; (US) (For US Only)
Inventors: ERTL, Hildegund, C., J.; (US).
WILSON, James, M.; (US)
Agent: KODROFF, Cathy, A.; Howson & Howson, Spring House Corporate Center, P.O. Box 457, Spring House, PA 19477 (US)
Priority Data:
60/300,131 22.06.2001 US
60/304,843 12.07.2001 US
Title (EN) METHODS OF INDUCING A CYTOTOXIC IMMUNE RESPONSE AND RECOMBINANT SIMIAN ADENOVIRUS COMPOSITIONS USEFUL THEREIN
(FR) PROCEDES VISANT A INDUIRE UNE REACTION IMMUNITAIRE CYTOTOXIQUE ET COMPOSITIONS D'ADENOVIRUS SIMIEN RECOMBINE UTILES A CET EFFET
Abstract: front page image
(EN)A method of inducing a CD8+ T response against a selected molecule by delivering the molecule via a recombinant simian adenovirus is provided. Also provided are methods of inducing interferon-α and interferon-β by delivering a recombinant simian adenovirus to a subject. The methods and compositions of the invention are particularly well suited for prophylaxis and treatment of infections with human immunodeficiency virus and human papilloma virus, among others, and cancer therapy.
(FR)Procédé visant à induire une réaction des lymphocytes T CD8+ contre une molécule sélectionnée, grâce à l'apport de cette molécule par l'intermédiaire d'un adénovirus simien recombiné. L'invention concerne aussi des procédés visant à induire une réaction d'interférons alpha et bêta par l'administration à un sujet d'un adénovirus simien recombiné. Les procédés et compositions de l'invention conviennent particulièrement bien pour prévenir et traiter des infections par le virus de l'immunodéficience humaine et le virus du papillome humain, entre autres, et comme traitement anticancéreux.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)