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1. (WO2003000185) COMPLEX MIXTURES EXHIBITING SELECTIVE INHIBITION OF CYCLOOXYGENASE-2
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2003/000185 International Application No.: PCT/US2002/019617
Publication Date: 03.01.2003 International Filing Date: 20.06.2002
IPC:
A61K 31/00 (2006.01) ,A61K 31/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
12
Ketones
Applicants: BABISH, John, G.[US/US]; US (UsOnly)
HOWELL, M., Terrence[US/US]; US (UsOnly)
METAPROTEOMICS, LLC[US/US]; 100 Avenida La Pata San Clemente, CA 92673, US (AllExceptUS)
Inventors: BABISH, John, G.; US
HOWELL, M., Terrence; US
Agent: McDERMOTT, WiLL & EMERY; 4370 La Jolla Village Drive 7th floor San Diego, CA 92122, US
Priority Data:
09/885,72120.06.2001US
Title (EN) COMPLEX MIXTURES EXHIBITING SELECTIVE INHIBITION OF CYCLOOXYGENASE-2
(FR) MELANGES COMPLEXES PERMETTANT L'INHIBITION SELECTIVE DE CYCLO-OXYGENASE-2
Abstract:
(EN) A novel formulation is provided that serves to specifically inhibit the COX-2 mediated inflammatory response in animals. The formulation comprises comprising an effective amount of component I selected from the group consisting of alpha acids and beta acids and an effective amount of at least one component II selected from the group consisting of alpha acids, beta acids, essential oils, fats and waxes, with the proviso that component I and II are not the same compound. The composition provides specific inhibition of cyclooxygenase-2 with little or no effect on cyclooxygenase-1.
(FR) L'invention concerne une nouvelle préparation capable, en particulier, d'inhiber la réponse inflammatoire induite par la COX-2 chez des animaux. La préparation comprend une quantité efficace d'un composant I choisi dans le groupe constitué d'acides alpha et d'acides bêta, et une quantité efficace d'au moins un composant II choisi dans le groupe constitué d'acides alpha, d'acides bêta, d'huiles essentielles, de graisses et de cires, pour autant que les composants I et II soient différents. La composition permet une inhibition spécifique de la cyclo-oxygénase-2 sans affecter, ou peu, la cyclo-oxygénase-1.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)