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1. (WO2003000118) METHOD FOR ENHANCING THE EFFECTIVENESS OF CANCER THERAPIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/000118    International Application No.:    PCT/US2002/019885
Publication Date: 03.01.2003 International Filing Date: 21.06.2002
Chapter 2 Demand Filed:    14.01.2003    
IPC:
A61K 31/00 (2006.01), A61K 31/732 (2006.01), A61K 45/06 (2006.01)
Applicants: GLYCOGENESYS, INC. [US/US]; 31 St. James Ave., 8th Floor, Boston, MA 02116 (US)
Inventors: CHANG, Yang; (US).
SASEK, Vodek; (US)
Agent: VINCENT, Matthew, P.; Ropes & Gray, Patent Group, One International Place, Boston, MA 02110 (US)
Priority Data:
60/299,991 21.06.2001 US
10/176,235 20.06.2002 US
Title (EN) METHOD FOR ENHANCING THE EFFECTIVENESS OF CANCER THERAPIES
(FR) AMELIORATION DE L'EFFICACITE DE THERAPIES ANTICANCEREUSES
Abstract: front page image
(EN)The efficacy of conventional cancer therapies such as surgery, chemotherapy and radiation is enhanced by the use of a therapeutic material which binds to and interacts with galectins. The therapeutic material can enhance apoptosis thereby increasing the effectiveness of oncolytic agents. It can also inhibit angiogenesis thereby moderating tumor growth and/or metastasis.
(FR)La présente invention concerne l'amélioration de l'efficacité de thérapies anticancéreuses conventionnelles (chirurgie, chimiothérapie, radiothérapie) par utilisation d'un matériau thérapeutique se liant aux galectines avec lesquelles il entre en interaction. Ce matériau thérapeutique peut renforcer l'apoptose et donc augmenter l'efficacité des oncolytiques. Il peut également inhiber l'angiogenèse et donc modérer la métastase et/ou la croissance tumorale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)