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1. (WO2003000114) CARBON MONOXIDE IMPROVES OUTCOMES IN TISSUE AND ORGAN TRANSPLANTS AND SUPPRESSES APOPTOSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2003/000114 International Application No.: PCT/US2002/019687
Publication Date: 03.01.2003 International Filing Date: 21.06.2002
Chapter 2 Demand Filed: 17.01.2003
IPC:
A61K 33/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
Applicants: BACH, Fritz, H.[US/US]; US (NZ, SG, US)
TOBIASCH, Edda, M.[DE/DE]; DE (NZ, SG, US)
SOARES, Miguel, C.[BE/PT]; PT (NZ, SG, US)
OTTERBEIN, Leo, E.[US/US]; US (NZ, SG, US)
GOSE, Jeanne[US/US]; US
BETH ISRAEL DEACONESS MEDICAL CENTER[US/US]; 330 Brookline Avenue Boston, MA 02215, US (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CR, CU, CY, CZ, DE, DK, DM, DZ, EE, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NE, NL, NO, PL, PT, RO, RU, SD, SE, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW)
YALE UNIVERSITY[US/US]; Two Whitney Avenue New Haven, CT 06511, US (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CR, CU, CY, CZ, DE, DK, DM, DZ, EE, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NE, NL, NO, PL, PT, RO, RU, SD, SE, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW)
Inventors: BACH, Fritz, H.; US
TOBIASCH, Edda, M.; DE
SOARES, Miguel, C.; PT
OTTERBEIN, Leo, E.; US
GOSE, Jeanne; US
Agent: FRASER, Janis, K.; Fish & Richardson 225 Franklin Street Boston, MA 02110-2804, US
Priority Data:
60/300,28921.06.2001US
60/334,34029.11.2001US
60/337,97407.12.2001US
Title (EN) CARBON MONOXIDE IMPROVES OUTCOMES IN TISSUE AND ORGAN TRANSPLANTS AND SUPPRESSES APOPTOSIS
(FR) UTILISATION DU MONOXYDE DE CARBONE POUR AMELIORER DES RESULTATS DANS DES TRANSPLANTATIONS DE TISSUS ET D'ORGANES ET SUPPRIMER L'APOPTOSE
Abstract:
(EN) The present invention features methods for transplanting organs, tissues and individual cells. Also featured are methods for maintaining cells $i(in vitro) and for enhancing survival and/or function of cells following transplantation. The methods include the administration of carbon monoxide in an amount sufficient to enhance cell survival and/or function.
(FR) L'invention se rapporte à des méthodes de transplantation d'organes, de tissus et de cellules individuelles. L'invention se rapporte également à des méthodes permettant de maintenir des cellules in vitro et d'accroître la survie et/ou la fonction des cellules après la transplantation. Les méthodes consistent en l'administration de monoxyde de carbone en une dose suffisante pour accroître la survie et/ou la fonction des cellules.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)