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1. WO2002100351 - A METHOD FOR TREATING INFLAMMATORY DISEASES BY ADMINISTERING A PPAR-DELTA AGONIST

Publication Number WO/2002/100351
Publication Date 19.12.2002
International Application No. PCT/US2002/020974
International Filing Date 07.06.2002
Chapter 2 Demand Filed 02.01.2003
IPC
A61K 45/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
CPC
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 13/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
A61P 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61P 17/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
A61P 17/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
06Antipsoriatics
Applicants
  • MERCK & CO., INC. [US]/[US] (AllExceptUS)
  • FORREST, Michael, J. [US]/[US] (UsOnly)
  • BERGER, Joel, P. [US]/[US] (UsOnly)
  • MOLLER, David, E. [US]/[US] (UsOnly)
  • WRIGHT, Samuel [US]/[US] (UsOnly)
Inventors
  • FORREST, Michael, J.
  • BERGER, Joel, P.
  • MOLLER, David, E.
  • WRIGHT, Samuel
Common Representative
  • MERCK & CO., INC.
Priority Data
60/297,35611.06.2001US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) A METHOD FOR TREATING INFLAMMATORY DISEASES BY ADMINISTERING A PPAR-DELTA AGONIST
(FR) PROCEDE DE TRAITEMENT DE MALADIES INFLAMMATOIRES PAR ADMINISTRATION D'UN AGONISTE PPAR-DELTA
Abstract
(EN) A method for treating, controlling, preventing or reducing the risk of contracting an inflammatory disease or condition in a mammalian patient, comprises the steps of (1) selecting a patient in need thereof, and (2) treating the patient with a therapeutically effective amount of a composition comprising a PPAR-$g(d) agonist. Inflammatory diseases that may be treated by this method include but are not limited to rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, degenerative joint disease, one or more connective tissue diseases, ankylosing spondylitis, and bursitis.
(FR) L'invention porte sur un procédé de traitement, contrôle, prévention ou réduction des risques de contraction d'une maladie ou état inflammatoire sur un patient mammalien. Ce procédé consiste à (1) sélectionner un patient et (2) le traiter avec une quantité efficace d'un point de vue thérapeutique d'une composition comprenant un agoniste PPAR-$g(d). Les maladies inflammatoires pouvant être traitées par ce procédé sont notamment, mais pas exclusivement, l'arthrite rhumatoïde, l'arthrite rhumatoïde juvénile, le lupus érythémateux disséminé, l'arthrose, la maladie des articulations dégénérative, une ou plusieurs maladies des tissus conjonctifs, la spondylarthrite ankylosante et la bursite.
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