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1. WO2002087481 - PREVENTION OF MYOCARDIAL INFARCTION INDUCED VENTRICULAR EXPANSION AND REMODELING

Publication Number WO/2002/087481
Publication Date 07.11.2002
International Application No. PCT/US2002/012976
International Filing Date 25.04.2002
Chapter 2 Demand Filed 25.11.2002
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
17
Surgical instruments, devices or methods, e.g. tourniquets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
17
Surgical instruments, devices or methods, e.g. tourniquets
03
for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith
04
for suturing wounds; Holders or packages for needles or suture materials
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
17
Surgical instruments, devices or methods, e.g. tourniquets
03
for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith
064
Surgical staples
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
17
Surgical instruments, devices or methods, e.g. tourniquets
03
for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith
068
Surgical staplers
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
17
Surgical instruments, devices or methods, e.g. tourniquets
34
Trocars; Puncturing needles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
24
Heart valves
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A61B 17/00 (2006.01)
A61B 17/04 (2006.01)
A61B 17/064 (2006.01)
A61B 17/068 (2006.01)
A61B 17/34 (2006.01)
A61F 2/00 (2006.01)
CPC
A61B 17/00234
A61B 17/00491
A61B 17/064
A61B 17/0644
A61B 17/068
A61B 17/3468
Applicants
  • MYOMEND, INC. [US/US]; 5 Commonwealth Road (Route 30) Suite 1C Natick, MA 01760, US (AllExceptUS)
  • SANTAMORE, William, P. [US/US]; US (UsOnly)
  • LESNIAK, Jeanne, M. [US/US]; US (UsOnly)
Inventors
  • SANTAMORE, William, P.; US
  • LESNIAK, Jeanne, M.; US
Agents
  • GARRETT, Arthur, S. ; Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P. 1300 I Street, N.W. Washington, DC 20260-3315, US
Priority Data
60/286,52127.04.2001US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PREVENTION OF MYOCARDIAL INFARCTION INDUCED VENTRICULAR EXPANSION AND REMODELING
(FR) PREVENTION D'INFARCTUS MYOCARDIQUE INDUITE PAR UNE EXPANSION ET UN REMODELAGE VENTRICULAIRE
Abstract
(EN)
A method for direct therapeutic treatment of myocardial tissue in a localized region of a heart having a pathological condition. The method includes identifying a target region of the myocardium and applying material directly and substantially only to at least a portion of the myocardial tissue of the target region. The material applied results in a physically modification the mechanical properties, including stiffness, of said tissue. Various devices and modes of practicing the method are disclosed for stiffening, restraining and constraining myocardial tissue for the treatment of conditions including myocardial infarction or mitral valve regurgitation.
(FR)
L'invention concerne un traitement thérapeutique direct d'un tissu myocardique dans une région localisée du coeur présentant un état pathologique. Une méthode consiste à identifier une région cible du myocarde et à appliquer un matériau directement et sensiblement uniquement sur une partie du tissu myocardique de la région cible. Le matériau appliqué entraîne une modification physique des propriétés mécaniques notamment de la rigidité du tissu. L'invention concerne également différents dispositifs et modes de pratique de ladite méthode permettant de raidir, de restreindre et de contraindre le tissu myocardique afin de traiter des états tels que l'infarctus myocardique et la régurgitation mitrale.
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