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1. WO2002066478 - ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE

Publication Number WO/2002/066478
Publication Date 29.08.2002
International Application No. PCT/GB2002/000677
International Filing Date 15.02.2002
Chapter 2 Demand Filed 18.08.2002
IPC
C07D 471/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
CPC
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • ASTRAZENECA AB [SE]/[SE] (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MK, ML, MN, MR, MW, MX, MZ, NE, NL, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW)
  • ASTRAZENECA UK LIMITED [GB]/[GB] (MG)
  • DOSSETTER, Alexander, Graham [GB]/[GB] (UsOnly)
  • KENNY, Peter [GB]/[GB] (UsOnly)
  • MCKERRECHER, Darren [GB]/[GB] (UsOnly)
  • WARDLEWORTH, Michael [GB]/[GB] (UsOnly)
Inventors
  • DOSSETTER, Alexander, Graham
  • KENNY, Peter
  • MCKERRECHER, Darren
  • WARDLEWORTH, Michael
Agents
  • BRYANT, Tracey, et al
Priority Data
0100568-520.02.2001SE
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE
(FR) ANTAGONISTES DE L'HORMONE DE LIBERATION DE LA GONADOTROPINE
Abstract
(EN)
The present invention relates to compounds of formula I which are antagonists of gonadotropin releasing hormone (GnRH) activity. The invention also relates to pharmaceutical formulations, the use of a compound of the present invention in the manufacture of a medicament, a method of therapeutic treatment using such a compound and processes for producing the compounds.
(FR)
La présente invention concerne des composés représentés par la formule I qui sont des antagonistes de l'hormone de libération de la gonadotropine (GnRH). L'invention concerne également des formulations pharmaceutiques, l'utilisation d'un composé de la présente invention pour la fabrication d'un médicament, une méthode de traitement à partir d'un tel composé et des procédés de fabrication de ces composés.
Also published as
Latest bibliographic data on file with the International Bureau