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1. (WO2002066459) INDOLE DERIVATIVES AND THEIR USE AS GNRH ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/066459    International Application No.:    PCT/GB2002/000679
Publication Date: 29.08.2002 International Filing Date: 15.02.2002
Chapter 2 Demand Filed:    16.08.2002    
IPC:
C07D 209/16 (2006.01), C07D 401/12 (2006.01), C07D 401/14 (2006.01), C07D 403/12 (2006.01), C07D 409/12 (2006.01), C07D 417/12 (2006.01), C07D 521/00 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; Sodertalje S-151 85 (SE) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, FR, GB, GD, GE, GH, GM, GR, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MK, MN, MW, MX, MZ, NL, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SZ, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW only).
ASTRAZENECA UK LIMITED [GB/GB]; 15 Stanhope Gate London, Greater London W1Y 6LN (GB) (MG only).
WARDLEWORTH, Michael [GB/GB]; (GB) (For US Only).
DOSSETTER, Alexander, Graham [GB/GB]; (GB) (For US Only).
HALSALL, Chris, T. [GB/GB]; (GB) (For US Only)
Inventors: WARDLEWORTH, Michael; (GB).
DOSSETTER, Alexander, Graham; (GB).
HALSALL, Chris, T.; (GB)
Agent: BRYANT, Tracey; AstraZeneca Global Intellectual Property Mereside Alderley Park Macclesfield, Cheshire SK10 4TG (GB)
Priority Data:
0100566-9 20.02.2001 SE
Title (EN) INDOLE DERIVATIVES AND THEIR USE AS GNRH ANTAGONISTS
(FR) DERIVES INDOLE ET LEUR UTILISATION EN TANT QU'ANTAGONISTES DE GNRH
Abstract: front page image
(EN)The present invention relates to compounds of formula (I) which are antagonists of gonadotropin releasing hormone (GnRH) activity. The invention also relates to pharmaceutical formulations, the use of a compound of the present invention in the manufacture of a medicament, a method of therapeutic treatment using such a compound and processes for producing the compounds.
(FR)La présente invention concerne des composés représentés par la formule I qui sont des antagonistes de l'hormone de libération de la gonadotropine (GnRH). L'invention concerne également des formulations pharmaceutiques, l'utilisation d'un composé de la présente invention pour la fabrication d'un médicament, une méthode de traitement à partir d'un tel composé et des procédés de fabrication de ces composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)