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1. WO2002041897 - NOVEL PHARMACEUTICAL COMPOSITIONS WITH ANTI-DIABETIC ACTIVITY AND METHOD FOR PREPARING SAME

Publication Number WO/2002/041897
Publication Date 30.05.2002
International Application No. PCT/FR2001/003697
International Filing Date 22.11.2001
IPC
A61K 31/155 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
155Amidines , e.g. guanidine , isourea , isothiourea
A61K 31/64 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
CPC
A61K 31/155
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
A61K 31/64
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applicants
  • LIPHA S.A. [FR]/[FR] (AllExceptUS)
  • CUGNARDEY, Nathalie [FR]/[FR] (UsOnly)
  • WIERNSPERGER, Nicolas [FR]/[FR] (UsOnly)
Inventors
  • CUGNARDEY, Nathalie
  • WIERNSPERGER, Nicolas
Agents
  • BURTIN, Jean-François
Priority Data
00/1506622.11.2000FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) NOVEL PHARMACEUTICAL COMPOSITIONS WITH ANTI-DIABETIC ACTIVITY AND METHOD FOR PREPARING SAME
(FR) COMPOSITIONS PHARMACEUTIQUES A ACTION ANTIDIABETIQUE CONSTITUES DE L'ASSOCIATION D'UN BIGUANIDE ET D'UN SULFONAMIDE
Abstract
(EN)
The invention relates to the field of therapeutic chemistry and more particularly to the production of novel medicines for treating diabetes. It specifically concerns novel anti-diabetic medicines consisting of a combination of two efficient active principles for oral administration, in subliminal doses, consisting of an anti-diabetic biguanidine and an anti-diabetic sulphonamide, combined or mixed with one or several inert pharmaceutically acceptable carriers. The invention further concerns a method for producing said medicines consisting of a biguanidine and a sulphonamide.
(FR)
La présente invention se rapporte au domaine de la chimie thérapeutique et plus particulièrement à la réalisation de nouveaux médicaments pour le traitement du diabète. Elle a spécifiquement pour objet de nouveaux médicaments antidiabétiques constitués d'une association de deux principes actifs efficaces par voie orale, à doses subliminaires, formés d'un biguanide antidiabétique et d'un sulfonamide antidiabétique, en association ou en mélange avec un ou plusieurs excipients inertes, pharmaceutiquement acceptables. L'invention se rapporte en outre à un procédé de réalisation de tels médicaments formés d'un biguanide et d'un sulfonamide.
Also published as
Latest bibliographic data on file with the International Bureau