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1. WO2002041840 - SILDENAFIL CITRATE CHEWING GUM FORMULATIONS AND METHODS OF USING THE SAME

Publication Number WO/2002/041840
Publication Date 30.05.2002
International Application No. PCT/US2001/046848
International Filing Date 13.11.2001
Chapter 2 Demand Filed 15.07.2002
IPC
A61K 9/68 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
68chewing gum type
A61K 31/519 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
CPC
A23G 4/06
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
06characterised by the composition ; containing organic or inorganic compounds
A23L 27/86
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
86Addition of bitterness inhibitors
A61K 31/519
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61K 9/0058
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0053Mouth and digestive tract, i.e. intraoral and peroral administration
0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
0058Chewing gums
A61P 15/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
10for impotence
Applicants
  • WM. WRIGLEY JR. COMPANY [US]/[US] (AllExceptUS)
  • GMUNDER, Charlean [US]/[US] (UsOnly)
  • LI, Weisheng [US]/[US] (UsOnly)
  • REAM, Ronald [US]/[US] (UsOnly)
Inventors
  • GMUNDER, Charlean
  • LI, Weisheng
  • REAM, Ronald
Agents
  • NIMZ, Jack, D.
Priority Data
09/714,57116.11.2000US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SILDENAFIL CITRATE CHEWING GUM FORMULATIONS AND METHODS OF USING THE SAME
(FR) FORMULATIONS DE GOMME A MACHER AU CITRATE DE SILDENAFIL ET PROCEDES D'UTILISATION
Abstract
(EN)
Methods and chewing gum formulations for delivering a medicament, namely sildenafil citrate, to an individual are provided. Further, an improved dosage form and method of treating erectile dysfunction are provided. Methods of treating esophageal spasms, dysphagia, and gastroparesis utilizing chewing gum formulations containing sildenafil citrate are also provided.
(FR)
La présente invention concerne des procédés et des formulations de gomme à mâcher permettant de délivrer un médicament, à savoir le citrate de sildénafil, à un individu. L'invention se rapporte également à une forme posologique et à un procédé de traitement de la dysfonction érectile améliorés. L'invention concerne enfin des procédés permettant de traiter les spasmes oesophagiens, la dysphagie et la gastroparèse à l'aide des formulations de gomme à mâcher contenant du citrate de sildénafil de l'invention.
Also published as
Latest bibliographic data on file with the International Bureau