Processing

Please wait...

Settings

Settings

Goto Application

1. WO2002039112 - IN VIVO DETECTION OF BIOMOLECULE CONCENTRATIONS USING FLUORESCENT TAGS

Publication Number WO/2002/039112
Publication Date 16.05.2002
International Application No. PCT/US2001/047373
International Filing Date 07.11.2001
Chapter 2 Demand Filed 20.02.2002
IPC
A61K 49/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
G01N 21/64 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
CPC
A61B 5/0071
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
0059using light, e.g. diagnosis by transillumination, diascopy, fluorescence
0071by measuring fluorescence emission
A61B 5/0084
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
0059using light, e.g. diagnosis by transillumination, diascopy, fluorescence
0082adapted for particular medical purposes
0084for introduction into the body, e.g. by catheters
A61K 49/0058
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
001Preparation for luminescence or biological staining
0013Luminescence
0017Fluorescence in vivo
005characterised by the carrier molecule carrying the fluorescent agent
0058Antibodies
Applicants
  • SICEL TECHNOLOGIES, INC. [US]/[US] (AllExceptUS)
  • BLACK, Robert, D. [US]/[US] (UsOnly)
Inventors
  • BLACK, Robert, D.
Agents
  • CROUSE, Robert, N.
Priority Data
60/247,57409.11.2000US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IN VIVO DETECTION OF BIOMOLECULE CONCENTRATIONS USING FLUORESCENT TAGS
(FR) PROCEDES, CIRCUITS ET COMPOSITIONS DE MATIERE CONÇUS POUR DETECTER IN VIVO DES CONCENTRATIONS BIOMOLECULAIRES A L'AIDE D'ETIQUETTES FLUORESCENTES
Abstract
(EN)
Methods are disclosed wherein labeled antibodies can be provided in vivo to tissue having antigens that specifically bind the labeled antibody. A first optical radiation is emitted into the tissue in vivo to excite the labeled antibody bound to the antigen in vivo. A second optical radiation that is emitted by the excited labeled antibody, in response to the excitation thereof, can be detected in vivo. Related telemetric circuits and compositions of matter are also disclosed.
(FR)
L'invention concerne des procédés qui permettent de fournir <i>in vivo</i> des anticorps étiquetés à des tissus ayant des antigènes qui lient spécifiquement l'anticorps étiqueté. Un premier rayonnement optique est émis à l'intérieur du tissu <i>in vivo</i> de façon à exciter l'anticorps lié à l'antigène <i>in vivo</i>. Un second rayonnement, émis par l'anticorps étiqueté excité, en réaction à l'excitation de celui-ci, peut être détecté <i>in vivo</i>. L'invention concerne également des circuits télémétriques et des compositions de matière.
Latest bibliographic data on file with the International Bureau