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1. (WO2002033053) METHOD FOR ENHANCING PRIMORDIAL GERM CELL NUMBER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/033053    International Application No.:    PCT/US2001/032516
Publication Date: 25.04.2002 International Filing Date: 17.10.2001
Chapter 2 Demand Filed:    14.05.2002    
IPC:
C12N 5/074 (2010.01), A61K 35/12 (2006.01)
Applicants: THE CURATORS OF THE UNIVERSITY OF MISSOURI [US/US]; 316 University Hall, Columbia, MO 65211 (US) (For All Designated States Except US).
ZHAO, Guang-Quan [US/US]; (US) (For US Only).
YING, Ying [US/US]; (US) (For US Only)
Inventors: ZHAO, Guang-Quan; (US).
YING, Ying; (US)
Agent: BLOSSER, G., Harley; Senniger, Powers, Leavitt & Roedel, One Metropolitan Square, 16th Floor, St. Louis, MO 63102 (US)
Priority Data:
60/241,395 18.10.2000 US
09/978,877 16.10.2001 US
Title (EN) METHOD FOR ENHANCING PRIMORDIAL GERM CELL NUMBER
(FR) PROCEDE D'AUGMENTATION DE NOMBRE DE CELLULES GERMINALES EMBRYONNAIRES
Abstract: front page image
(EN)Methods for enhancing the generation of primordial germ cells in pluripotent embryonic cells by contacting the pluripotent cells with at least one 60A class BMP protein and at least one DPP class BMP protein are provided. Also provided are methods for treating sterility and for the introduction of at least one transgene into the germ line of an animal.
(FR)La présente invention concerne des procédés pour améliorer la génération de cellules germinales embryonnaires dans des cellules embryonnaires pluripotentielles par la mise en contact des cellules pluripotentielles avec au moins une protéine morphogénétique osseuse de classe 60A et au moins une protéine morphogénétique osseuse de classe Drosophila décapentaplégique (DPP). L'invention concerne également des procédés de traitement de la stérilité et d'insertion d'au moins un transgène dans la ligne cellulaire germinale d'un animal.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)