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1. (WO2002032896) FURAZANYL-TRIAZOLE DERIVATES FOR THE TREATMENT OF DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/032896    International Application No.:    PCT/DK2001/000676
Publication Date: 25.04.2002 International Filing Date: 12.10.2001
Chapter 2 Demand Filed:    13.04.2002    
IPC:
A61K 31/4192 (2006.01), A61K 31/4245 (2006.01), A61K 31/443 (2006.01), A61K 31/4439 (2006.01), A61K 31/496 (2006.01), A61K 31/5355 (2006.01), A61K 31/55 (2006.01), A61P 3/10 (2006.01), A61P 25/18 (2006.01), A61P 25/24 (2006.01), A61P 25/28 (2006.01), C07D 413/04 (2006.01), C07D 413/14 (2006.01)
Applicants: NOVO NORDISK A/S [DK/DK]; Corporate Patents, Novo Allé, DK-2880 Bagsværd (DK) (For All Designated States Except US).
OLESEN, Preben, Houlberg [DK/DK]; (DK) (For US Only).
KURTZHALS, Peter [DK/DK]; (DK) (For US Only).
WORSAAE, Helle [DK/DK]; (DK) (For US Only).
HANSEN, Bo, Falck [DK/DK]; (DK) (For US Only).
SØRENSEN, Anders, Robert [DK/DK]; (DK) (For US Only).
BOWLER, Andrew, Neil [GB/DK]; (DK) (For US Only)
Inventors: OLESEN, Preben, Houlberg; (DK).
KURTZHALS, Peter; (DK).
WORSAAE, Helle; (DK).
HANSEN, Bo, Falck; (DK).
SØRENSEN, Anders, Robert; (DK).
BOWLER, Andrew, Neil; (DK)
Common
Representative:
NOVO NORDISK A/S; Corporate Patents, Novo Allé, DK-2880 Bagsværd (DK)
Priority Data:
PA 2000 01537 16.10.2000 DK
60/242,409 20.10.2000 US
Title (EN) FURAZANYL-TRIAZOLE DERIVATES FOR THE TREATMENT OF DISEASES
(FR) DERIVES DE FURAZANYL-TRIAZOLE DESTINES AU TRAITEMENT DE MALADIES
Abstract: front page image
(EN)Pharmaceutical compositions comprising 1-(furazanyl-3-yl)-[1,2,3]triazole derivatives of the general formula (I) wherein the meanings of R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ and n are as given in the description, for the treatment and/or prevention of disorders and diseases, wherein an inhibition of GSK-3 (glycogen synthase kinase-3) is beneficial, especially Alzheimer's disease, bipolar disorder, IGT (impaired glucose tolerance), Type 1 diabetes, Type 2 diabetes and obesity.
(FR)L'invention concerne des compositions pharmaceutiques comportant des dérivés de 1-(furazan-3-yl)-[1,2,3] triazole de la formule générale (I) dans laquelle R?1¿,R?2¿,R?3¿,R?4¿,R?5 ¿et n ont la notation donnée dans la description, destinées au traitement et/ou à la prévention de troubles et de maladies, et présentant une inhibition favorable de la GSK-3 (glycogène synthase kinase-3), en particulier pour le traitement de la maladie d'Alzheimer, d'un trouble bipolaire, de l'IGT (tolérance réduite au glucose), des diabètes de type 1 et de type 2, et de l'obésité.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)