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Machine translation
1. (WO2002032881) NOVEL REMEDIES OR PREVENTIVES FOR ANGIOSTENOSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/032881    International Application No.:    PCT/JP2001/009131
Publication Date: 25.04.2002 International Filing Date: 18.10.2001
Chapter 2 Demand Filed:    15.03.2002    
IPC:
A61K 31/505 (2006.01), A61K 31/506 (2006.01), C07D 239/36 (2006.01)
Applicants: NIPPON KAYAKU KABUSHIKI KAISHA [JP/JP]; 11-2, Fujimi 1-chome Chiyoda-ku, Tokyo 102-8172 (JP) (For All Designated States Except US).
MIYAZAKI, Mizuo [JP/JP]; (JP) (For US Only).
KAMOSHITA, Keiichi [JP/JP]; (JP) (For US Only).
SUKENAGA, Yoshikazu [JP/JP]; (JP) (For US Only).
SUZUKI, Yoshikazu [JP/JP]; (JP) (For US Only)
Inventors: MIYAZAKI, Mizuo; (JP).
KAMOSHITA, Keiichi; (JP).
SUKENAGA, Yoshikazu; (JP).
SUZUKI, Yoshikazu; (JP)
Agent: SAEKI, Norio; 9th floor, Taka-ai Building 15-2, Nihonbashi 3-chome Chuo-ku, Tokyo 103-0027 (JP)
Priority Data:
2000-318832 19.10.2000 JP
2001-282509 18.09.2001 JP
Title (EN) NOVEL REMEDIES OR PREVENTIVES FOR ANGIOSTENOSIS
(FR) NOUVEAUX AGENTS THERAPEUTIQUES OU PROPHYLACTIQUES CONTRE L'ANGIOSTENOSE
Abstract: front page image
(EN)Remedies or preventives for angiostenosis which comprise as the active ingredient a compound having a pyrimidone skeleton and having a chymase inhibitory activity, for example, a compound having the skeleton structure represented by the following formula (II): and having a highly selective chymase activity or its pharmacologically acceptable salt. These drugs are characterized by being usable in oral administration.
(FR)Agents thérapeutiques ou prophylactiques contre l'angiosténose contenant, en tant qu'ingrédient actif, un composé possédant un squelette de pyrimidone et exerçant une activité d'inhibition de chymase, notamment, composé dont la structure de squelette est représentée par la formule (II), ce composé exerçant une activité de chymase extrêmement sélective, ou un de ses sels acceptables sur le plan pharmacologique. Ces agents peuvent être administrés par voie orale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)