WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2002031166) ARTIFICIAL TRANSCRIPTIONAL FACTORS AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/031166    International Application No.:    PCT/US2001/032000
Publication Date: 18.04.2002 International Filing Date: 15.10.2001
Chapter 2 Demand Filed:    10.05.2002    
IPC:
C12N 15/11 (2006.01), C12N 15/63 (2006.01)
Applicants: CROSSLINK GENETICS CORPORATION [US/US]; One Kendall Square, Building 600, PMB 255, Cambridge, MA 02139 (US)
Inventors: STANOJEVIC, Dusan; (US)
Agent: SCOZZAFAVA, MaryRose; Hale and Dorr LLP, 60 State Street, Boston, MA 02109 (US)
Priority Data:
60/240,479 13.10.2000 US
Title (EN) ARTIFICIAL TRANSCRIPTIONAL FACTORS AND METHODS OF USE
(FR) FACTEURS TRANSCRIPTIONNELS ARTIFICIELS ET LEURS METHODES D'UTILISATION
Abstract: front page image
(EN)An artificial transcription factors (ATF) is provided having a non-peptidic-DNA binding domain, flexible linker and a short synthetic effector domain. The ATFs are highly potent transcriptional modulators in vitro and in vivo. Methods for targeted manipulation of gene expression and the development of new class of pharmaceuticals are also provided.
(FR)L'invention concerne des facteurs transcriptionnels artificiels (ATF) possédant un domaine de liaison d'ADN non peptidique, un liant souple, et un domaine effecteur synthétique court. Les ATF sont des modulateurs transcriptionnels hautement efficaces <i>in vitro</i> et <i>in vivo</i>. L'invention concerne également des méthodes permettant d'effectuer une manipulation d'expression génique ciblée et de développer une nouvelle classe de substances pharmaceutiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)