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Pub. No.:    WO/2002/030506    International Application No.:    PCT/IL2001/000941
Publication Date: 18.04.2002 International Filing Date: 11.10.2001
A61M 37/00 (2006.01)
Applicants: INK JET TECHNOLOGY LTD. [IL/IL]; Harakevet Street 27 93502 Jerusalem (IL) (For All Designated States Except US).
CARMON, Amiram [IL/IL]; (IL) (For US Only).
ROSENBERG-HAGEN, Benyamina [IL/IL]; (IL) (For US Only).
ROSENMANN, Eliezer [IL/IL]; (IL) (For US Only)
Inventors: CARMON, Amiram; (IL).
ROSENMANN, Eliezer; (IL)
Agent: REINHOLD COHN AND PARTNERS; P.O. Box 4060 61040 Tel Aviv (IL)
Priority Data:
138963 12.10.2000 IL
142076 19.03.2001 IL
Abstract: front page image
(EN)A method for transport through a skin surface comprising (i) applying a microdosing device to the skin surface, (ii) ejecting from the device a keratolytic agent onto the skin surface thereby forming at least one blister containing interstitial fluid, and (iii) transporting an active agent into the blister, transporting interstitial fluid from the blister, or both. The keratolytic agent is not cantharidine. Also disclosed is a microdosing device comprising at least two sets of conduits, a first set capable of ejecting an keratolytic agent and a second set capable of transporting a liquid.
(FR)La présente invention concerne un procédé de transport à travers la surface de la peau, qui consiste à : (i) appliquer un dispositif de microdosage sur la surface de la peau ; (ii) éjecter du dispositif un agent kératolytique jusque sur la surface de la peau de façon à former au moins une cloque contenant du liquide interstitiel ; et (iii) transporter un agent actif jusque dans la cloque et/ou transporter le liquide interstitiel hors de la cloque. L'agent kératolytique précité n'est pas la cantharidine. L'invention se rapporte également à un dispositif de microdosage comprenant au moins deux jeux de conduits, un premier jeu capable d'éjecter un agent kératolytique et un second jeu capable de transporter un liquide.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)