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1. (WO2002029041) 32146 AND 57259, NOVEL HUMAN TRANSPORTERS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/029041    International Application No.:    PCT/US2001/031412
Publication Date: 11.04.2002 International Filing Date: 05.10.2001
Chapter 2 Demand Filed:    11.04.2002    
IPC:
C07K 14/47 (2006.01)
Applicants: MILLENNIUM PHARMACEUTICALS, INC. [US/US]; 75 Sidney Street, Cambridge, MA 02139 (US) (For All Designated States Except US).
CURTIS, Rory, A., J. [GB/US]; (US) (For US Only)
Inventors: CURTIS, Rory, A., J.; (US)
Agent: PAGLIERANI, Paul; Millennium Pharmaceuticals, Inc., 75 Sidney Street, Cambridge, MA 02139 (US)
Priority Data:
60/238,336 05.10.2000 US
Title (EN) 32146 AND 57259, NOVEL HUMAN TRANSPORTERS AND USES THEREOF
(FR) 32146 ET 57259, NOUVEAUX TRANSPORTEURS HUMAINS ET LEURS UTILISATIONS
Abstract: front page image
(EN)The invention provides isolated nucleic acids molecules, designated TFM-2 and TFM-3 nucleic acid molecules, which encode novel transporter family molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing TFM-2 and/or TFM-3 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a TFM-2 and/or TFM-3 gene has been introduced or disrupted. The invention still further provides isolated TFM-2 and TFM-3 polypeptides, fusion polypeptides, antigenic peptides and anti-TFM-2 and anti-TFM-3 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
(FR)L'invention concerne des molécules d'acides nucléiques isolées appelées molécules d'acides nucléiques TFM-2 et TFM-3, qui codent de nouvelles molécules de la famille des transporteurs. L'invention concerne également des molécules d'acide nucléique antisens, des vecteurs d'expression recombinés contenant des molécules d'acides nucléiques TFM-2 et/ou TFM-3, des cellules hôtes dans lesquelles ont été introduits ces vecteurs d'expression, et des animaux transgéniques non humains dans lesquels un gène TFM-2 et/ou TFM-3 a été introduit ou interrompu. L'invention concerne en outre des polypeptides TFM-2 et TFM-3 isolés, des polypeptides de fusion, des peptides antigéniques et des anticorps anti-TFM-2 et anti-TFM-3. L'invention concerne enfin des méthodes diagnostiques utilisant les compositions selon l'invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)