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1. (WO2002028372) SYSTEMIC DELIVERY OF COMPOUNDS THROUGH NON-INVASIVE BLADDER ADMINISTRATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/028372    International Application No.:    PCT/US2001/031739
Publication Date: 11.04.2002 International Filing Date: 05.10.2001
Chapter 2 Demand Filed:    29.04.2002    
IPC:
A61K 9/16 (2006.01), A61K 9/51 (2006.01), A61K 38/19 (2006.01), A61K 39/39 (2006.01)
Applicants: JOHNS HOPKINS UNIVERSITY [US/US]; Suite 906, 111 Market Place, Baltimore, MD 21202 (US)
Inventors: LEONG, Kam, W.; (US).
HALLER, Michael, F.; (US).
MALAVAUD, Bernard, A.; (FR).
LEVISAGE, Catherine, S.; (US)
Agent: CORLESS, Peter, F.; Dike, Bronstein, Roberts & Cushman, Intellectual Property Practice Group, Edwards & Angell, LLP, P.O. Box 9169, Boston, MA 02209 (US)
Priority Data:
60/238,505 06.10.2000 US
Title (EN) SYSTEMIC DELIVERY OF COMPOUNDS THROUGH NON-INVASIVE BLADDER ADMINISTRATION
(FR) DELIVRANCE SYSTEMIQUE DE COMPOSES PAR ADMINISTRATION NON-INVASIVE PAR LA VESSIE
Abstract: front page image
(EN)The present invention features methods of administering a therapeutic agent to a patient's lymph nodes by instillation of microparticles or nanoparticles comprising a biocompatible polymer and the therapeutic agent into the patient's bladder. The invention also features methods of modulating a patient's immune response and methods of systemic delivery of a therapeutic agent systematically using the administration methods of the invention.
(FR)La présente invention concerne des procédés d'administration d'un agent thérapeutique aux ganglions lymphatiques d'un patient par injection de microparticules ou de nanoparticules comportant un polymère biocompatible et l'agent thérapeutique dans la vessie du patient. L'invention concerne également des procédés de modulation de la réponse immunitaire d'un patient et des procédés de délivrance systémiques d'un agent thérapeutique utilisant de manière systématique les méthodes d'administration de l'invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)