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Machine translation
1. (WO2002027296) QUANTITATIVE DIGITAL FLUOROGRAPHY AND RELATED PRODUCTS AND METHODS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/027296    International Application No.:    PCT/US2001/042219
Publication Date: 04.04.2002 International Filing Date: 17.09.2001
Chapter 2 Demand Filed:    26.04.2002    
IPC:
G01N 1/22 (2006.01), G01N 15/00 (2006.01), G01N 15/14 (2006.01), G01N 21/64 (2006.01), G01N 35/00 (2006.01)
Applicants: HYPERION, INC. [US/US]; 14100 S.W. 136th Street, Miami, FL 33186 (US) (For All Designated States Except US).
BOTZ, Eduard, J. [AT/US]; (US) (For US Only).
RANA, Victoriano, F. [US/US]; (US) (For US Only).
NEWTON, Kenneth, R. [US/US]; (US) (For US Only).
LIN, Tsue-Ming [US/US]; (US) (For US Only)
Inventors: BOTZ, Eduard, J.; (US).
RANA, Victoriano, F.; (US).
NEWTON, Kenneth, R.; (US).
LIN, Tsue-Ming; (US)
Agent: BROOK, Mitchell, P.; Baker & McKenzie, Twelfth Floor, 101 West Broadway, San Diego, CA 92101 (US).
TRICE, Ronald, G.; Baker & McKenzie, 2001 Ross Avenue, Suite 2300, Dallas, TX 75201 (US)
Priority Data:
09/671,956 27.09.2000 US
Title (EN) QUANTITATIVE DIGITAL FLUOROGRAPHY AND RELATED PRODUCTS AND METHODS
(FR) FLUOROGRAPHIE NUMERIQUE QUANTITATIVE ET TECHNIQUES ET PRODUITS ASSOCIES
Abstract: front page image
(EN)The present invention thus relates to marker components, fluorescent probes, oligonucleotides, hybridization assays, and binding assays such as immunoassays, DNA assays and receptor assays using such products and methods for making such products. According to the present invention, delectably labeled marker components are provided thus comprise a fluorophore moiety coupled to two or more small solubilizing axial ligands, which preferably reduce or remove the problems of solvent sensibility and non-specific binding.
(FR)La présente invention concerne des composants marqueurs, des sondes fluorescentes, des oligonucléotides, des essais d'hybridation et des analyses de liaison, notamment des immuno-essais, des analyses d'ADN et des analyses de récepteurs utilisant de tels produits, ainsi que des techniques destinées à fabriquer ces produits. La présente invention se rapporte également à des composants marqueurs marqués de manière détectable et comprenant une entité fluorophore couplée à deux ou plusieurs petits ligands axiaux solubilisants. De préférence, ces ligands permettent de réduire ou d'éliminer les problèmes de sensibilité au solvant et de liaison non spécifique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)